Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20715145 | 0.88 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL15837580 | 0.87 | HTR2A (0.36) | NCF1HTR2AHTR2C | |
| SCHEMBL22245179 | 0.82 | — | — | |
| SCHEMBL20711788 | 0.79 | PIK3CA (0.35) | — | |
| SCHEMBL21625313 | 0.77 | HRH3 (0.33) | — | |
| SCHEMBL12324 | 0.76 | NCF1 (0.34) | NCF1HTR2AHTR2C | |
| SCHEMBL14022395 | 0.76 | NCF1 (0.34) | NCF1HTR2AHTR2C | |
| SCHEMBL20609823 | 0.74 | NCF1 (0.38) | NCF1 | |
| SCHEMBL17052883 | 0.74 | NCF1 (0.38) | NCF1 | |
| SCHEMBL13621103 | 0.74 | LMNA (0.43) | NCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019027960-A1 | PYRAZOLO AND TRIAZOLO BICYCLIC COMPOUNDS AS JAK KINASE INHIBITORS | THERAVANCE BIOPHARMA R&D IP, LLC (US) | 2019-02-07 | — | — | WO | disclosed |