Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MMP1 | P03956 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | MME | P08473 | 2/20 | 0.33 |
| ▸ | ACE | P12821 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CPA1 | P15085 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14588571 | 1.00 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2AFAAHMAPK1 | |
| SCHEMBL21661003 | 0.82 | SPHK1 (0.37) | ALDH1A1MEN1KMT2AFAAHMAPK1 | |
| SCHEMBL21661358 | 0.82 | SPHK1 (0.37) | ALDH1A1MEN1KMT2AFAAHMAPK1 | |
| SCHEMBL24482433 | 0.80 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2AFAAHMAPK1 | |
| SCHEMBL12733455 | 0.80 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2ALMNAMMP2 | |
| SCHEMBL19498585 | 0.80 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2ALMNAMMP2 | |
| SCHEMBL13625078 | 0.78 | CTSS (0.33) | TSHRMMEUSP2LONP1 | |
| SCHEMBL23617776 | 0.78 | CTSS (0.33) | TSHRMMEUSP2LONP1 | |
| SCHEMBL19245403 | 0.78 | — | — | |
| SCHEMBL15834073 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019027960-A1 | PYRAZOLO AND TRIAZOLO BICYCLIC COMPOUNDS AS JAK KINASE INHIBITORS | THERAVANCE BIOPHARMA R&D IP, LLC (US) | 2019-02-07 | — | — | WO | disclosed |