SCHEMBL20716046

SCHEMBL20716046

Cc1ccc(N2C(=O)c3ccc(C#Cc4ccccc4)cc3C2=O)cc1

nearest known ligand 0.55

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.55
NPC1 O15118 1/20 0.55
TSHR P16473 1/20 0.55
CASP1 P29466 1/20 0.55
RAB9A P51151 1/20 0.55
CASP7 P55210 1/20 0.55
HSD17B10 Q99714 1/20 0.55
CA9 Q16790 3/20 0.54
CA12 O43570 2/20 0.54
CA1 P00915 2/20 0.54
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
CA2 P00918 1/20 0.49
GRM5 P41594 5/20 0.49
ESR1 P03372 1/20 0.49
POLB P06746 1/20 0.48
HPGD P15428 1/20 0.48
ADORA2A P29274 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16927161 0.94 GRM5 (0.54) ALDH1A1NPC1TSHRCASP1RAB9A
SCHEMBL13703631 0.92 GRM5 (0.48) ALDH1A1NPC1TSHRCASP1RAB9A
SCHEMBL7678431 0.91 ESR1 (0.58) ALDH1A1CA9CA12CA1MEN1
SCHEMBL2625350 0.90 GRM5 (0.48) ALDH1A1NPC1TSHRCASP1RAB9A
SCHEMBL84247 0.88 MEN1 (0.58) ALDH1A1NPC1TSHRCASP1RAB9A
SCHEMBL10000450 0.87 MAPK1 (0.53) ALDH1A1CA9CA12CA1MEN1
SCHEMBL2471106 0.87 ESR1 (0.63) CA9CA12CA1MEN1KMT2A
SCHEMBL13900322 0.86 CA9 (0.55) ALDH1A1NPC1TSHRCASP1RAB9A
SCHEMBL10000443 0.86 MEN1 (0.56) ALDH1A1NPC1TSHRCASP1RAB9A
SCHEMBL9967357 0.85 CA9 (0.51) ALDH1A1HSD17B10CA9CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11001013-B2 Pre-preg and composite products comprising fibers and a liquid crystal thermoset precursor ALLOTROPICA TECHNOLOGIES INC. (US) 2021-05-11 US disclosed
US-20190039331-A1 PRE-PREG AND COMPOSITE PRODUCTS COMPRISING FIBERS AND A LIQUID CRYSTAL THERMOSET PRECURSOR ALLOTROPICA TECHNOLOGIES INC. 2019-02-07 US disclosed