Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | CCR3 | P51677 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8936204 | 0.82 | OPRL1 (0.46) | OPRL1MEN1KMT2APOLBSIGMAR1 | |
| SCHEMBL24696382 | 0.81 | OPRL1 (0.45) | OPRL1MEN1KMT2APOLBSIGMAR1 | |
| SCHEMBL8663255 | 0.81 | OPRL1 (0.45) | OPRL1MEN1KMT2APOLBSIGMAR1 | |
| SCHEMBL5067826 | 0.80 | MEN1 (0.46) | OPRL1MEN1KMT2APOLBSIGMAR1 | |
| SCHEMBL12672699 | 0.79 | MEN1 (0.45) | OPRL1MEN1KMT2APOLBSIGMAR1 | |
| SCHEMBL5592149 | 0.79 | OPRL1 (0.46) | OPRL1MEN1KMT2APOLBSIGMAR1 | |
| SCHEMBL3272543 | 0.78 | MEN1 (0.47) | OPRL1MEN1KMT2APOLBSIGMAR1 | |
| SCHEMBL5466208 | 0.76 | KMT2A (0.46) | OPRL1MEN1KMT2APOLBSIGMAR1 | |
| SCHEMBL2931788 | 0.76 | MEN1 (0.46) | OPRL1MEN1KMT2APOLBSIGMAR1 | |
| SCHEMBL25000121 | 0.76 | CYP2D6 (0.43) | OPRL1MEN1KMT2APOLBSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8829218-B2 | Highly active and selective ethylene oligomerization catalyst and method of preparing hexene or octene using the same | SK INNOVATION CO., LTD. (KR) | 2014-09-09 | — | — | US | disclosed |
| EP-1405852-B9 | DIAMINE DERIVATIVES | DAIICHI SANKYO CO LTD (JP) | 2013-03-27 | — | — | EP | disclosed |
| EP-2543682-A1 | HIGHLY ACTIVE AND HIGHLY SELECTIVE ETHYLENE OLIGOMERIZATION CATALYST, AND PREPARATION METHOD OF HEXENE OR OCTENE USING SAME | SK Innovation Co. Ltd. (KR) | 2013-01-09 | — | — | EP | disclosed |
| EP-1405852-B1 | DIAMINE DERIVATIVES | DAIICHI SANKYO CO LTD (JP) | 2012-08-01 | — | — | EP | disclosed |
| US-20120130086-A1 | Highly Active and Selective Ethylene Oligomerization Catalyst and Method of Preparing Hexene or Octene Using the Same | SK GLOBAL CHEMICAL CO., LTD. (KR) | 2012-05-24 | — | — | US | disclosed |
| US-8088796-B2 | Triamine derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-01-03 | — | — | US | disclosed |
| US-20110312990-A1 | Diamine Derivatives | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-12-22 | — | — | US | disclosed |
| EP-2343290-A1 | Diamine derivatives as factor X inhibitors | Daiichi Sankyo Company, Limited (JP) | 2011-07-13 | — | — | EP | disclosed |
| US-20110077266-A1 | Diamine Derivatives | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-03-31 | — | — | US | disclosed |
| US-20100099660-A1 | METHOD FOR TREATING THROMBOSIS OR EMBOLISM AND RELATED DISEASES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2010-04-22 | — | — | US | disclosed |
| US-7365205-B2 | Cyclic diamine derivatives useful as agents for preventing and/or treating cerebral infarction, cerebral embolism, myocardial infarction, angina pectoris, pulmonary infarction, pulmonary embolism; inhibit activated blood coagulation factor X | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2008-04-29 | — | — | US | disclosed |
| US-7342014-B2 | Diamine derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2008-03-11 | — | — | US | disclosed |
| US-20080015215-A1 | DIAMINE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2008-01-17 | — | — | US | disclosed |
| US-20060252837-A1 | Cyclic diamine derivatives useful as agents for preventing and/or treating cerebral infarction, cerebral embolism, myocardial infarction, angina pectoris, pulmonary infarction, pulmonary embolism; inhibit activated blood coagulation factor X | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-11-09 | — | — | US | disclosed |
| US-20050245565-A1 | Diamine derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2005-11-03 | — | — | US | disclosed |
| EP-1577301-A1 | DIAMINE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2005-09-21 | — | — | EP | disclosed |
| US-20050119486-A1 | Diamine derivatives | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2005-06-02 | — | — | US | disclosed |
| US-20050020645-A1 | Diamine derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2005-01-27 | — | — | US | disclosed |
| EP-1415992-A1 | DIAMINE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-05-06 | — | — | EP | disclosed |
| EP-1405852-A1 | DIAMINE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-04-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120130086-A1 | Highly Active and Selective Ethylene Oligomerization Catalyst and Method of Preparing Hexene or Octene Using the Same | ORC3, OXER1, EXOC1 | OPRL1 2323/4885MEN1 695/4885KMT2A 2985/4885 |
| US-20100099660-A1 | METHOD FOR TREATING THROMBOSIS OR EMBOLISM AND RELATED DISEASES | F2, PLAT, MPL | OPRL1 2718/4885MEN1 322/4885KMT2A 2546/4885 |
| US-20060252837-A1 | Cyclic diamine derivatives useful as agents for preventing and/or treating cerebral infarction, cerebral embolism, myocardial infarction, angina pectoris, pulmonary infarction, pulmonary embolism; inhibit activated blood coagulation factor X | F2, C1S, C9 | OPRL1 1013/4885MEN1 726/4885KMT2A 3495/4885 |
| US-20050020645-A1 | Diamine derivatives | C9, C1S, C1R | OPRL1 573/4885MEN1 457/4885KMT2A 3485/4885 |
| US-20080015215-A1 | DIAMINE DERIVATIVES | C9, C1S, C1R | OPRL1 573/4885MEN1 457/4885KMT2A 3485/4885 |
| US-20050245565-A1 | Diamine derivatives | C9, C1S, C1R | OPRL1 573/4885MEN1 457/4885KMT2A 3485/4885 |
| US-20050119486-A1 | Diamine derivatives | C9, C1S, C1R | OPRL1 573/4885MEN1 457/4885KMT2A 3485/4885 |
| US-20110077266-A1 | Diamine Derivatives | F2, TFPI, F3 | OPRL1 4235/4885MEN1 1094/4885KMT2A 1453/4885 |
| US-20110312990-A1 | Diamine Derivatives | C9, C1S, C1R | OPRL1 487/4885MEN1 602/4885KMT2A 3461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.