Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3272543 | 0.84 | MEN1 (0.47) | MEN1KMT2ASIGMAR1CYP3A4HSD17B10 | |
| SCHEMBL9301631 | 0.81 | MEN1 (0.45) | MEN1KMT2ASIGMAR1CYP3A4HSD17B10 | |
| SCHEMBL8936204 | 0.81 | OPRL1 (0.46) | MEN1KMT2ASIGMAR1CYP3A4HSD17B10 | |
| SCHEMBL5592149 | 0.81 | OPRL1 (0.46) | MEN1KMT2ASIGMAR1CYP3A4HSD17B10 | |
| SCHEMBL24696382 | 0.79 | OPRL1 (0.45) | MEN1KMT2ASIGMAR1CYP3A4HSD17B10 | |
| SCHEMBL26619967 | 0.79 | SIGMAR1 (0.44) | MEN1KMT2ASIGMAR1CYP3A4HSD17B10 | |
| SCHEMBL14827664 | 0.78 | MEN1 (0.43) | MEN1KMT2ASIGMAR1CYP3A4HSD17B10 | |
| SCHEMBL25000121 | 0.78 | CYP2D6 (0.43) | MEN1KMT2ASIGMAR1CYP3A4CYP2D6 | |
| SCHEMBL24316045 | 0.78 | MEN1 (0.43) | MEN1KMT2ASIGMAR1CYP3A4HSD17B10 | |
| SCHEMBL31105377 | 0.78 | CYP2D6 (0.43) | MEN1KMT2ASIGMAR1CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1611131-B1 | PYRAZOLOPYRIDINE DERIVATES | PALAU PHARMA SA (ES) | 2010-09-15 | — | — | EP | disclosed |