SCHEMBL20717853

SCHEMBL20717853

N#COC[C@H]1CC[C@@H](COC#N)CC1

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CTSL P07711 1/20 0.34
CTSB P07858 1/20 0.34
CTSK P43235 1/20 0.34
SIGMAR1 Q99720 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20717666 1.00 CTSL (0.34) CTSLCTSBCTSKSIGMAR1
SCHEMBL19157990 1.00 CTSL (0.34) CTSLCTSBCTSKSIGMAR1
SCHEMBL25059864 0.92 KMT2A (0.34) CTSLCTSBCTSK
SCHEMBL5473537 0.88
SCHEMBL20433010 0.88
SCHEMBL2336763 0.87 CTSK (0.48) CTSLCTSBCTSK
SCHEMBL25059941 0.83
SCHEMBL24404207 0.82 KMT2A (0.33)
SCHEMBL17299358 0.82 KMT2A (0.30)
SCHEMBL23130548 0.79 CTSL (0.38) CTSLCTSBCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230002540-A1 FOAMED POLYURETHANE COMPOSITIONS PRESIDIUM INNOVATIONS, LLC 2023-01-05 US disclosed
US-20210363290-A1 POLYOL COMPOSITIONS PRESIDIUM USA INC (US) 2021-11-25 US disclosed
EP-3580258-B1 OLIGOMERIC POLYOL COMPOSITIONS PRESIDIUM USA INC (US) 2021-08-11 EP disclosed
US-11078325-B2 Method of preparing polyurethanes from oligomeric polyol compositions and polyisocyanates PRESIDIUM USA, INC (US) 2021-08-03 US disclosed
US-11072680-B2 Composition comprising oligomeric polyol compositions and polyisocyanates PRESIDIUM USA, INC. (US) 2021-07-27 US disclosed
US-11072679-B2 Polyurethanes prepared from oligomeric polyol compositions and polyisocyanates PRESIDIUM USA, INC (US) 2021-07-27 US disclosed
US-11066511-B2 Oligomeric polyol compositions PRESIDIUM USA, INC. (US) 2021-07-20 US disclosed
US-11066512-B2 Method of preparing oligomeric polyol compositions PRESIDIUM USA, INC. (US) 2021-07-20 US disclosed
US-20190241699-A1 Method of Preparing Polyurethanes From Oligomeric Polyol Compositions and Polyisocyanates PRESIDIUM INNOVATIONS, LLC 2019-08-08 US disclosed
US-20190055345-A1 Polyurethanes Prepared from Oligomeric Polyol Compositions and Polyisocyanates PRESIDIUM INNOVATIONS, LLC 2019-02-21 US disclosed
US-20190055346-A1 Method of Preparing Oligomeric Polyol Compositions PRESIDIUM INNOVATIONS, LLC 2019-02-21 US disclosed
US-20190040184-A1 OLIGOMERIC POLYOL COMPOSITIONS PRESIDIUM INNOVATIONS, LLC 2019-02-07 US disclosed