Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.45 |
| ▸ | INSR | P06213 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20718563 | 0.89 | KDM4E (0.52) | KDM4EALDH1A1INSRMEN1KMT2A | |
| SCHEMBL20718569 | 0.79 | INSR (0.49) | KDM4EALDH1A1ERBB2INSRMEN1 | |
| SCHEMBL20718565 | 0.79 | INSR (0.49) | KDM4EALDH1A1ERBB2INSRMEN1 | |
| SCHEMBL20718363 | 0.75 | INSR (0.49) | KDM4EALDH1A1ERBB2INSRMEN1 | |
| SCHEMBL20718359 | 0.73 | INSR (0.46) | KDM4EALDH1A1ERBB2INSRMEN1 | |
| SCHEMBL19918086 | 0.73 | KDM4E (0.67) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL1199113 | 0.68 | KDM4E (0.67) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL12328697 | 0.68 | KDM4E (0.63) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL6545560 | 0.68 | KDM4E (0.63) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL17322556 | 0.68 | INSR (0.75) | ALDH1A1INSRMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019025595-A1 | SELECTIVE LIGANDS FOR TAU AGGREGATES | KARIN & STEN MORTSTEDT CBD SOLUTIONS AB (SE) | 2019-02-07 | — | — | WO | disclosed |