Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | INSR | P06213 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20718365 | 0.89 | KDM4E (0.49) | KDM4EALDH1A1RXRAMEN1KMT2A | |
| SCHEMBL20718600 | 0.78 | ADRB2 (0.52) | KDM4EALDH1A1MEN1KMT2AHTT | |
| SCHEMBL20718568 | 0.78 | ADRB2 (0.46) | KDM4EALDH1A1MEN1KMT2AHTT | |
| SCHEMBL19918086 | 0.75 | KDM4E (0.67) | KDM4EALDH1A1RXRAMEN1KMT2A | |
| SCHEMBL20718562 | 0.73 | ADRB2 (0.46) | KDM4EALDH1A1MEN1KMT2AHTT | |
| SCHEMBL20718564 | 0.72 | ADRB2 (0.51) | KDM4EALDH1A1MEN1KMT2AHTT | |
| SCHEMBL20718002 | 0.71 | MAPT (0.58) | KDM4EALDH1A1MEN1KMT2AHTT | |
| SCHEMBL1199113 | 0.70 | KDM4E (0.67) | KDM4EALDH1A1RXRAMEN1KMT2A | |
| SCHEMBL6545560 | 0.70 | KDM4E (0.63) | KDM4EALDH1A1RXRAMEN1KMT2A | |
| SCHEMBL12328697 | 0.70 | KDM4E (0.63) | KDM4EALDH1A1RXRAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019025595-A1 | SELECTIVE LIGANDS FOR TAU AGGREGATES | KARIN & STEN MORTSTEDT CBD SOLUTIONS AB (SE) | 2019-02-07 | — | — | WO | disclosed |