Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | STAT1 | P42224 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2324097 | 0.93 | HTT (0.55) | ALDH1A1KDM4EHTTNPC1MAPT | |
| SCHEMBL28577903 | 0.91 | HTT (0.53) | ALDH1A1KDM4EHTTNPC1MAPT | |
| SCHEMBL21981938 | 0.84 | HTT (0.67) | ALDH1A1KDM4EHTTNPC1MAPT | |
| SCHEMBL18914368 | 0.82 | HTT (0.49) | ALDH1A1KDM4EHTTNPC1MAPT | |
| SCHEMBL29952713 | 0.81 | KDM4E (0.59) | ALDH1A1KDM4ENPC1MAPTRAB9A | |
| SCHEMBL4399339 | 0.80 | KDM4E (0.72) | ALDH1A1KDM4ENPC1MAPTRAB9A | |
| SCHEMBL18914742 | 0.80 | HTT (0.46) | ALDH1A1KDM4EHTTNPC1MAPT | |
| SCHEMBL26078289 | 0.79 | SMN1; SMN2 (0.58) | ALDH1A1HTTNPC1MAPTRAB9A | |
| SCHEMBL69791 | 0.78 | HTT (0.69) | ALDH1A1KDM4EHTTNPC1MAPT | |
| SCHEMBL6656195 | 0.78 | ALDH1A1 (0.61) | ALDH1A1KDM4EHTTNPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200369659-A1 | SELECTIVE LIGANDS FOR TAU AGGREGATES | CBD SOLUTIONS AB (SE) | 2020-11-26 | — | — | US | disclosed |
| WO-2019025595-A1 | SELECTIVE LIGANDS FOR TAU AGGREGATES | KARIN & STEN MORTSTEDT CBD SOLUTIONS AB (SE) | 2019-02-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200369659-A1 | SELECTIVE LIGANDS FOR TAU AGGREGATES | MAPT, PSEN1, PSEN2 | ALDH1A1 3634/4885KDM4E 4702/4885HTT 17/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.