Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2324097 | 0.98 | HTT (0.55) | HTTALDH1A1KDM4EMEN1CYP1A2 | |
| SCHEMBL20718445 | 0.91 | ALDH1A1 (0.63) | HTTALDH1A1KDM4EMEN1CYP1A2 | |
| SCHEMBL18914368 | 0.87 | HTT (0.49) | HTTALDH1A1KDM4EMEN1CYP1A2 | |
| SCHEMBL18914742 | 0.85 | HTT (0.46) | HTTALDH1A1KDM4EMEN1CYP1A2 | |
| SCHEMBL1530931 | 0.81 | HTT (0.53) | HTTALDH1A1KDM4EMEN1CYP1A2 | |
| SCHEMBL26078289 | 0.80 | SMN1; SMN2 (0.58) | HTTALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL69791 | 0.80 | HTT (0.69) | HTTALDH1A1KDM4EMEN1CYP1A2 | |
| SCHEMBL16670649 | 0.79 | HTT (0.50) | HTTALDH1A1KDM4EMEN1CYP1A2 | |
| SCHEMBL2926770 | 0.79 | MAPT (0.60) | HTTALDH1A1KDM4ENPSR1LMNA | |
| SCHEMBL1185540 | 0.79 | ALDH1A1 (0.40) | HTTALDH1A1KDM4ELMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112979596-A | Method for preparing dimethyl 2, 5-furandicarboxylate | 中国科学院大连化学物理研究所 | 2021-06-18 | — | — | CN | disclosed |