Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | PNMT | P11086 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 7/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20699974 | 0.84 | DRD1 (0.49) | MAPTHTTADRA2AADRA2BADRA2C | |
| SCHEMBL20703561 | 0.83 | TAAR1 (0.55) | MAPTHTTADRA2AADRA2BADRA2C | |
| SCHEMBL20700301 | 0.83 | TAAR1 (0.55) | MAPTHTTADRA2AADRA2BADRA2C | |
| SCHEMBL8549512 | 0.83 | MAPT (0.38) | MAPTHTTADRA2AADRA2BADRA2C | |
| SCHEMBL5090707 | 0.81 | PNMT (0.41) | MAPTHTTPNMTHTR2ASLC6A4 | |
| SCHEMBL5088620 | 0.81 | PNMT (0.41) | MAPTHTTPNMTHTR2ASLC6A4 | |
| SCHEMBL7092032 | 0.81 | MAPT (0.38) | MAPTHTTADRA2APNMTADRA2B | |
| SCHEMBL5093605 | 0.79 | MAPT (0.43) | MAPTHTTSRD5A1ALDH1A1THRB | |
| SCHEMBL5090662 | 0.79 | MAPT (0.43) | MAPTHTTSRD5A1ALDH1A1THRB | |
| SCHEMBL28745705 | 0.79 | MAPT (0.39) | MAPTHTTSRD5A1HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019028165-A1 | ISOCHROMAN COMPOUNDS AND USES THEREOF | SUNOVION PHARMACEUTICALS INC. (US) | 2019-02-07 | — | — | WO | disclosed |