Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | DHPS | P49366 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29981309 | 0.91 | MGLL (0.35) | ADRA2AADRA1AGPR119SCN9ASCN5A | |
| SCHEMBL20700136 | 0.91 | MGLL (0.35) | ADRA2AADRA1AGPR119SCN9ASCN5A | |
| SCHEMBL20699928 | 0.91 | MGLL (0.35) | ADRA2AADRA1AGPR119SCN9ASCN5A | |
| SCHEMBL20700434 | 0.91 | MGLL (0.35) | ADRA2AADRA1AGPR119SCN9ASCN5A | |
| SCHEMBL29981103 | 0.90 | GPR119 (0.36) | ADRA2AADRA1AGPR119SCN9ASCN5A | |
| SCHEMBL20700509 | 0.90 | GPR119 (0.36) | ADRA2AADRA1AGPR119SCN9ASCN5A | |
| SCHEMBL29981178 | 0.90 | GPR119 (0.36) | ADRA2AADRA1AGPR119SCN9ASCN5A | |
| SCHEMBL20700039 | 0.90 | GPR119 (0.36) | ADRA2AADRA1AGPR119SCN9ASCN5A | |
| SCHEMBL20700037 | 0.90 | GPR119 (0.36) | ADRA2AADRA1AGPR119SCN9ASCN5A | |
| SCHEMBL20699941 | 0.90 | GPR119 (0.34) | GPR119PTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019028165-A1 | ISOCHROMAN COMPOUNDS AND USES THEREOF | SUNOVION PHARMACEUTICALS INC. (US) | 2019-02-07 | — | — | WO | disclosed |