Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23384545 | 0.83 | S1PR1 (0.42) | ITGB3ITGA2BS1PR1CYP1A2HIF1A | |
| SCHEMBL20739606 | 0.82 | HPGD (0.51) | HPGDKMT2ALMNA | |
| SCHEMBL20722178 | 0.82 | HPGD (0.51) | HPGDKMT2ALMNA | |
| SCHEMBL20739480 | 0.82 | S1PR1 (0.44) | ITGB3ITGA2BS1PR1CYP2D6CYP1A2 | |
| SCHEMBL23384541 | 0.81 | S1PR1 (0.41) | ITGB3ITGA2BS1PR1CYP1A2HIF1A | |
| SCHEMBL23357638 | 0.80 | S1PR1 (0.37) | ITGB3ITGA2BS1PR1HSD17B10ALDH1A1 | |
| SCHEMBL20722200 | 0.80 | S1PR1 (0.37) | ITGB3ITGA2BS1PR1HSD17B10ALDH1A1 | |
| SCHEMBL20722167 | 0.80 | S1PR1 (0.37) | ITGB3ITGA2BS1PR1HSD17B10ALDH1A1 | |
| SCHEMBL23384542 | 0.80 | ITGB3 (0.42) | ITGB3ITGA2BS1PR1HPGDCYP2D6 | |
| SCHEMBL20723272 | 0.79 | SPHK1 (0.47) | S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019032631-A1 | OXIME ETHER COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-02-14 | — | — | WO | disclosed |