Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | GPR183 | P32249 | 9/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20739606 | 1.00 | HPGD (0.51) | HPGDGPR183CA12CA1CA2 | |
| SCHEMBL20739480 | 0.86 | S1PR1 (0.44) | CA12CA1CA2CA7CA9 | |
| SCHEMBL23384545 | 0.83 | S1PR1 (0.42) | CA12CA1CA2CA7CA9 | |
| SCHEMBL20722167 | 0.83 | S1PR1 (0.37) | SMN1; SMN2 | |
| SCHEMBL23357638 | 0.83 | S1PR1 (0.37) | SMN1; SMN2 | |
| SCHEMBL20722200 | 0.83 | S1PR1 (0.37) | SMN1; SMN2 | |
| SCHEMBL20722161 | 0.82 | ITGB3 (0.40) | HPGDKMT2ALMNA | |
| SCHEMBL23384541 | 0.81 | S1PR1 (0.41) | — | |
| SCHEMBL23384542 | 0.80 | ITGB3 (0.42) | HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL20723272 | 0.77 | SPHK1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019032631-A1 | OXIME ETHER COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-02-14 | — | — | WO | disclosed |