Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 7/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20723785 | 1.00 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2ACETHRBALOX12 | |
| SCHEMBL2873012 | 0.82 | ACE (0.35) | ALDH1A1SMN1; SMN2ACE | |
| SCHEMBL2873008 | 0.82 | ACE (0.35) | ALDH1A1SMN1; SMN2ACE | |
| SCHEMBL2698663 | 0.82 | ACE (0.35) | ALDH1A1SMN1; SMN2ACE | |
| SCHEMBL15542290 | 0.82 | — | — | |
| SCHEMBL5224593 | 0.82 | — | — | |
| SCHEMBL5223810 | 0.82 | — | — | |
| SCHEMBL30838604 | 0.77 | HPGD (0.36) | ALDH1A1 | |
| SCHEMBL30838611 | 0.77 | HPGD (0.36) | ALDH1A1 | |
| SCHEMBL21224905 | 0.77 | ACE (0.41) | ACEREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019032941-A1 | LINCOSAMIDE ANTIBIOTICS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-02-14 | — | — | WO | disclosed |