Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.37 |
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18716564 | 0.79 | SLC6A2 (0.41) | SLC6A2SLC6A4DRD3CHRM1OPRM1 | |
| SCHEMBL18716619 | 0.78 | FUCA1 (0.35) | — | |
| SCHEMBL10361267 | 0.78 | SLC6A2 (0.43) | SLC6A2SLC6A4DRD3CHRM1OPRM1 | |
| Hydrochloric Acid SCHEMBL11056736 | 0.77 | SLC6A2 (0.42) | SLC6A2SLC6A4DRD3CHRM1OPRM1 | |
| SCHEMBL4667127 | 0.75 | LMNA (0.40) | SLC6A2SLC6A4DRD3CHRM1OPRM1 | |
| SCHEMBL11051916 | 0.75 | LMNA (0.40) | SLC6A2SLC6A4DRD3CHRM1OPRM1 | |
| SCHEMBL25706023 | 0.74 | SCN9A (0.34) | — | |
| SCHEMBL3301280 | 0.73 | SLC6A2 (0.38) | SLC6A2SLC6A4DRD3CHRM1OPRM1 | |
| SCHEMBL24081431 | 0.72 | — | — | |
| SCHEMBL17752564 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3150598-B1 | SUBSTITUTED TROPANE DERIVATIVES | TOA EIYO LTD (JP) | 2019-02-13 | — | — | EP | disclosed |