Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11051916 | 1.00 | LMNA (0.40) | LMNASLC6A2CHRM1DRD3SLC6A4 | |
| SCHEMBL6616685 | 0.79 | MAPK1 (0.48) | LMNASLC6A2CHRM1DRD3SLC6A4 | |
| SCHEMBL3301280 | 0.78 | SLC6A2 (0.38) | LMNASLC6A2CHRM1DRD3SLC6A4 | |
| SCHEMBL7689846 | 0.76 | LMNA (0.39) | LMNASLC6A2CHRM1DRD3SLC6A4 | |
| SCHEMBL10361267 | 0.75 | SLC6A2 (0.43) | LMNASLC6A2CHRM1DRD3SLC6A4 | |
| SCHEMBL20725546 | 0.75 | SLC6A2 (0.43) | LMNASLC6A2CHRM1DRD3SLC6A4 | |
| SCHEMBL4820734 | 0.73 | OPRM1 (0.41) | SLC6A2CHRM1DRD3SLC6A4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11056736 | 0.73 | SLC6A2 (0.42) | LMNASLC6A2CHRM1DRD3SLC6A4 | |
| SCHEMBL27877298 | 0.72 | PRCP (0.37) | SLC6A2DRD3CHRM2 | |
| SCHEMBL18716564 | 0.72 | SLC6A2 (0.41) | LMNASLC6A2CHRM1DRD3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1434604-A4 | 4-HALOETHENYLPHENYL TROPANE:SEROTONIN TRANSPORTER IMAGING AGENTS | UNIV EMORY (US) | 2008-01-09 | — | — | EP | disclosed |
| US-6843979-B2 | 4-haloethenylphenyl tropane:serotonin transporter imaging agents | EMORY UNIVERSITY (US) | 2005-01-18 | — | — | US | disclosed |
| EP-1434604-A2 | 4-HALOETHENYLPHENYL TROPANE:SEROTONIN TRANSPORTER IMAGING AGENTS | Emory University (US) | 2004-07-07 | — | — | EP | disclosed |
| WO-2003031452-A2 | 4-HALOETHENYLPHENYL TROPANE:SEROTONIN TRANSPORTER IMAGING AGENTS | EMORY UNIVERSITY (US) | 2003-04-17 | — | — | WO | disclosed |
| US-20020099184-A1 | 4-Haloethenyphenyl tropane:serotonin transporter imaging agents | ENERGY, UNITED STATES DEPARTMENT OF | 2002-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020099184-A1 | 4-Haloethenyphenyl tropane:serotonin transporter imaging agents | SLC6A4, SLC6A2, SLC6A3 | LMNA 4370/4885SLC6A2 2/4885CHRM1 1323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.