Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | DGKA | P23743 | 1/20 | 0.35 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26034603 | 1.00 | TSHR (0.45) | TSHRCYP3A4MEN1THRBHTT | |
| SCHEMBL26034669 | 0.92 | MEN1 (0.52) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL26034440 | 0.81 | CYP3A4 (0.53) | TSHRCYP3A4ALDH1A1ATM | |
| SCHEMBL4264802 | 0.80 | — | — | |
| SCHEMBL26034654 | 0.79 | EPHX2 (0.37) | MEN1KMT2AALDH1A1 | |
| SCHEMBL13017482 | 0.79 | CES2 (0.50) | TSHRCYP3A4MEN1THRBHTT | |
| SCHEMBL16581259 | 0.79 | HSD17B10 (0.32) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL20725788 | 0.79 | CYP1A2 (0.31) | CYP3A4MAPT | |
| SCHEMBL9651246 | 0.78 | — | — | |
| SCHEMBL17909689 | 0.77 | AKR1B1 (0.58) | TSHRCYP3A4MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3441382-A1 | OXA ACID COMPOUND | Moresco Corporation (JP) | 2019-02-13 | — | — | EP | disclosed |