⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9651246 | 0.92 | — | — | |
| SCHEMBL13903246 | 0.90 | CES2 (0.56) | — | |
| SCHEMBL5126821 | 0.90 | CES2 (0.56) | — | |
| SCHEMBL4802270 | 0.90 | CES2 (0.56) | — | |
| SCHEMBL1257720 | 0.90 | CES2 (0.56) | — | |
| SCHEMBL1367103 | 0.90 | CES2 (0.56) | — | |
| SCHEMBL4803397 | 0.90 | CES2 (0.56) | — | |
| SCHEMBL1365133 | 0.90 | CES2 (0.56) | — | |
| SCHEMBL20648076 | 0.90 | CES2 (0.56) | — | |
| SCHEMBL25526352 | 0.90 | CES2 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4268811-A1 | NOVEL DERIVATIVE COMPOUND HAVING BIPHENYL GROUP INTRODUCED INTO AMINO-ALKANOIC ACID AND ANTI-INFLAMMATORY COMPOSITION COMPRISING SAME | Amtixbio Co., Ltd. (KR) | 2023-11-01 | — | — | EP | disclosed |
| WO-2021161099-A1 | PROCESS FOR THE SYNTHESIS OF S-BEFLUBUTAMID FROM (R)-2-AMINOBUTANOIC ACID | CHEMINOVA A/S (DK) | 2021-08-19 | — | — | WO | disclosed |
| US-10227330-B2 | Diaminopyrimidine derivatives and processes for the preparation thereof | YUHAN CORPORATION (KR) | 2019-03-12 | — | — | US | disclosed |
| US-20180111918-A1 | DIAMINOPYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2018-04-26 | — | — | US | disclosed |
| US-9890138-B2 | Diaminopyrimidine derivatives and processes for the preparation thereof | YUHAN CORPORATION (KR) | 2018-02-13 | — | — | US | disclosed |
| US-20170231227-A1 | ANTIFUNGAL-GRAFTED POLYOLEFIN | SHIN JOONGMIN (US) | 2017-08-17 | — | — | US | disclosed |
| US-20150274700-A2 | DIAMINOPYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2015-10-01 | — | — | US | disclosed |
| WO-2014164844-A1 | CATHEPSIN INHIBITORS | VIROBAY, INC. (US) | 2014-10-09 | — | — | WO | disclosed |
| US-20130338179-A1 | DIAMINOPYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2013-12-19 | — | — | US | disclosed |
| US-8518916-B2 | Heterocyclic derivatives as M-GLU5 antagonists | RECORDATI IRELAND LIMITED (IE) | 2013-08-27 | — | — | US | disclosed |
| CN-101969946-A | Novel crystalline forms of 4- [4- (2-adamantylcarbamoyl) -5-tert-butyl-pyrazol-1-yl ] benzoic acid | ASTRAZENECA AB | 2011-02-09 | — | — | CN | disclosed |
| US-20090042841-A1 | NOVEL HETEROCYCLIC DERIVATIVES AS M-GLU5 ANTAGONISTS | RECORDATI IRELAND LIMITED (IE) | 2009-02-12 | — | — | US | disclosed |