Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.56 |
| ▸ | NPC1 | O15118 | 7/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 2/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | FBP1 | P09467 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11100838 | 0.82 | RAB9A (0.51) | RAB9ANPC1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL7899328 | 0.78 | RAB9A (0.64) | RAB9ANPC1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL128647 | 0.75 | AGPAT2 (0.56) | RAB9ANPC1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL3822363 | 0.74 | RAB9A (0.59) | RAB9ANPC1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL23933064 | 0.74 | RAB9A (0.55) | RAB9ANPC1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL12162629 | 0.74 | RAB9A (0.55) | RAB9ANPC1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL13788541 | 0.73 | PIK3CA (0.49) | — | |
| SCHEMBL13436713 | 0.72 | RAB9A (0.66) | RAB9ANPC1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL128635 | 0.72 | FBP1 (0.61) | RAB9ANPC1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL10223594 | 0.71 | RAB9A (0.54) | RAB9ANPC1MAPTKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3441392-A1 | A PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION | Intellikine, LLC (US) | 2019-02-13 | — | — | EP | disclosed |