Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.51 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.51 |
| ▸ | ACE | P12821 | 6/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.49 |
| ▸ | MME | P08473 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | CPA1 | P15085 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | IL2 | P60568 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1081372 | 0.87 | FOLH1 (0.54) | FOLH1NAALAD2ACESLC7A5MME | |
| SCHEMBL31533362 | 0.87 | FOLH1 (0.54) | FOLH1NAALAD2ACESLC7A5MME | |
| SCHEMBL31533361 | 0.87 | FOLH1 (0.54) | FOLH1NAALAD2ACESLC7A5MME | |
| SCHEMBL1081373 | 0.87 | FOLH1 (0.54) | FOLH1NAALAD2ACESLC7A5MME | |
| SCHEMBL23704504 | 0.84 | FOLH1 (0.51) | FOLH1NAALAD2ACESLC7A5MME | |
| SCHEMBL29746410 | 0.84 | FOLH1 (0.51) | FOLH1NAALAD2ACESLC7A5MME | |
| SCHEMBL246177 | 0.84 | FOLH1 (0.51) | FOLH1NAALAD2ACESLC7A5MME | |
| SCHEMBL10778599 | 0.81 | FOLH1 (0.55) | FOLH1NAALAD2ACESLC7A5MME | |
| SCHEMBL8414223 | 0.81 | FOLH1 (0.55) | FOLH1NAALAD2ACESLC7A5MME | |
| SCHEMBL2214358 | 0.81 | FOLH1 (0.55) | FOLH1NAALAD2ACESLC7A5MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012025464-A1 | FLUORODEUTERIOMETHYL TYROSINE DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-03-01 | — | — | WO | disclosed |