Sugi Predict

Sugi Predict / Compounds / SCHEMBL246177

SCHEMBL246177

SCHEMBL246177

O=C(O)[C@H](Cc1ccc(O)cc1)NCCF

nearest known ligand 0.51

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 1/20 0.51
▸ NAALAD2 Q9Y3Q0 1/20 0.51
▸ ACE P12821 6/20 0.50
▸ SLC7A5 Q01650 1/20 0.49
▸ MME P08473 5/20 0.48
▸ MEN1 O00255 2/20 0.48
▸ KMT2A Q03164 2/20 0.48
▸ L3MBTL1 Q9Y468 2/20 0.48
▸ CPA1 P15085 1/20 0.47
▸ ACE2 Q9BYF1 1/20 0.47
▸ CA1 P00915 2/20 0.46
▸ CA2 P00918 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23704504 1.00 FOLH1 (0.51) FOLH1NAALAD2ACESLC7A5MME
SCHEMBL29746410 1.00 FOLH1 (0.51) FOLH1NAALAD2ACESLC7A5MME
SCHEMBL27973851 0.91 FOLH1 (0.49) FOLH1NAALAD2ACESLC7A5MME
SCHEMBL31533361 0.87 FOLH1 (0.54) FOLH1NAALAD2ACESLC7A5MME
SCHEMBL1081373 0.87 FOLH1 (0.54) FOLH1NAALAD2ACESLC7A5MME
SCHEMBL31533362 0.87 FOLH1 (0.54) FOLH1NAALAD2ACESLC7A5MME
SCHEMBL1081372 0.87 FOLH1 (0.54) FOLH1NAALAD2ACESLC7A5MME
SCHEMBL6443925 0.84 FOLH1 (0.55) FOLH1NAALAD2ACESLC7A5MME
SCHEMBL6443921 0.84 FOLH1 (0.55) FOLH1NAALAD2ACESLC7A5MME
SCHEMBL20726 0.84 FOLH1 (0.51) FOLH1NAALAD2ACESLC7A5MME

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250049409-A1 METHODS OF QUANTIFYING SKELETAL MUSCLE PERFUSION USING PET IMAGING RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL 2025-02-13 — — US claimed
JP-2012500036-A — — 2012-01-05 — — JP claimed
EP-2318970-A2 MODEL ENHANCED IMAGING Koninklijke Philips Electronics N.V. (NL) 2011-05-11 — — EP claimed
WO-2010018477-A2 MODEL ENHANCED IMAGING KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2010-02-18 — — WO claimed
WO-2026104860-A2 ACTIVATABLE BINDING MOLECULE CAMBRIDGE ENTERPRISE LIMITED (GB) 2026-05-21 — — WO disclosed
US-20260137765-A1 METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STXB) MONOMERS AND OLIGOMERS, AND USES THEREOF INSTITUT CURIE (FR) 2026-05-21 — — US disclosed
US-12527854-B2 Methods of producing Shiga toxin B-subunit (STxB) monomers and oligomers, and uses thereof INSTITUT CURIE (FR) 2026-01-20 — — US disclosed
US-20250339712-A1 ADAPTIVE CORRELATION FILTER FOR RADIOTHERAPY REFLEXION MEDICAL INC (US) 2025-11-06 — — US disclosed
EP-4619094-A1 ADAPTIVE CORRELATION FILTER FOR RADIOTHERAPY RefleXion Medical, Inc. (US) 2025-09-24 — — EP disclosed
US-20250281535-A1 ANTI-HUMAN CD45RC BINDING DOMAINS AND USES THEREOF ABOLERIS PHARMA (FR) 2025-09-11 — — US disclosed
EP-4401842-B1 ANTI-HUMAN CD45RC BINDING DOMAINS AND USES THEREOF ABOLERIS PHARMA (FR) 2025-08-27 — — EP disclosed
US-20250122300-A1 ANTI-HUMAN CD45RC ANTIBODIES AND USES THEREOF INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2025-04-17 — — US disclosed
US-20110299747-A1 FUNCTIONAL IMAGING KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2011-12-08 — — US disclosed
WO-2010106449-A2 FUNCTIONAL IMAGING KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2010-09-23 — — WO disclosed
US-20090041664-A1 5-Pyrrolidinylsulfonyl Isatin Derivatives UNIVERSITATSKLINIKUM MUNSTER (DE) 2009-02-12 — — US disclosed
EP-1841759-A2 5-PYRROLIDINYLSULFONYL ISATIN DERIVATIVES Universitätsklinikum Münster (DE) 2007-10-10 — — EP disclosed
US-20070071671-A1 Process for producing radioactive-fluorine-labeled compound NIHON MEDI-PHYSICS CO., LTD. (JP) 2007-03-29 — — US disclosed
US-20070036258-A1 Process for producing radioactive fluorine compound NIHON MEDI-PHYSICS CO., LTD. (JP) 2007-02-15 — — US disclosed
EP-1683776-A1 PROCESS FOR PRODUCING RADIOACTIVE-FLUORINE-LABELED COMPOUND Nihon Medi-Physics Co., Ltd. (JP) 2006-07-26 — — EP disclosed
WO-2006074799-A2 5-PYRROLIDINYLSULFONYL ISATIN DERIVATIVES Universitätsklinikum Münster (DE) 2006-07-20 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12527854-B2 Methods of producing Shiga toxin B-subunit (STxB) monomers and oligomers, and uses thereof STXBP1, RNGTT, UPF1 FOLH1 3283/4885NAALAD2 2969/4885ACE 3069/4885
US-20260137765-A1 METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STXB) MONOMERS AND OLIGOMERS, AND USES THEREOF STXBP1, HBB, UPF1 FOLH1 2969/4885NAALAD2 3490/4885ACE 3166/4885
US-20090041664-A1 5-Pyrrolidinylsulfonyl Isatin Derivatives CASP5, CTSZ, CTSS FOLH1 105/4885NAALAD2 509/4885ACE 1535/4885
US-20070071671-A1 Process for producing radioactive-fluorine-labeled compound PFAS, PFKFB3, PFKFB2 FOLH1 2691/4885NAALAD2 880/4885ACE 3657/4885
US-20070036258-A1 Process for producing radioactive fluorine compound AFF1, AFF4, RER1 FOLH1 3303/4885NAALAD2 4195/4885ACE 4032/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.