SCHEMBL29746410

SCHEMBL29746410

O=C(O)[C@H](Cc1ccc(O)cc1)NCC[18F]

nearest known ligand 0.51

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 1/20 0.51
NAALAD2 Q9Y3Q0 1/20 0.51
ACE P12821 6/20 0.50
SLC7A5 Q01650 1/20 0.49
MME P08473 5/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
CPA1 P15085 1/20 0.47
ACE2 Q9BYF1 1/20 0.47
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL246177 1.00 FOLH1 (0.51) FOLH1NAALAD2ACESLC7A5MME
SCHEMBL23704504 1.00 FOLH1 (0.51) FOLH1NAALAD2ACESLC7A5MME
SCHEMBL27973851 0.91 FOLH1 (0.49) FOLH1NAALAD2ACESLC7A5MME
SCHEMBL31533361 0.87 FOLH1 (0.54) FOLH1NAALAD2ACESLC7A5MME
SCHEMBL1081373 0.87 FOLH1 (0.54) FOLH1NAALAD2ACESLC7A5MME
SCHEMBL31533362 0.87 FOLH1 (0.54) FOLH1NAALAD2ACESLC7A5MME
SCHEMBL1081372 0.87 FOLH1 (0.54) FOLH1NAALAD2ACESLC7A5MME
SCHEMBL6443925 0.84 FOLH1 (0.55) FOLH1NAALAD2ACESLC7A5MME
SCHEMBL6443921 0.84 FOLH1 (0.55) FOLH1NAALAD2ACESLC7A5MME
SCHEMBL20726 0.84 FOLH1 (0.51) FOLH1NAALAD2ACESLC7A5MME

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250082768-A1 CONJUGATING REAGENTS AND CONJUGATES THEREOF CAMBRIDGE ENTERPRISE LIMITED (GB) 2025-03-13 US disclosed
US-12078625-B2 System and method for high-throughput radio thin layer chromatography analysis THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-09-03 US disclosed
US-20220244228-A1 SYSTEM AND METHOD FOR HIGH-THROUGHPUT RADIO THIN LAYER CHROMATOGRAPHY ANALYSIS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-08-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250082768-A1 CONJUGATING REAGENTS AND CONJUGATES THEREOF PA2G4, CD47, IGLV6-57 FOLH1 525/4885NAALAD2 302/4885ACE 3346/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.