Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR2C2 | P49116 | 4/20 | 0.48 |
| ▸ | TAB1 | Q15750 | 4/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.48 |
| ▸ | RELA | Q04206 | 3/20 | 0.48 |
| ▸ | SYK | P43405 | 2/20 | 0.48 |
| ▸ | KDR | P35968 | 3/20 | 0.45 |
| ▸ | FLT1 | P17948 | 2/20 | 0.45 |
| ▸ | FLT4 | P35916 | 2/20 | 0.45 |
| ▸ | IGF1R | P08069 | 3/20 | 0.44 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | SMG1 | Q96Q15 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | PLK4 | O00444 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2374752 | 0.78 | NR2C2 (0.65) | NR2C2TAB1NFKB1NFKB2RELA | |
| SCHEMBL30806995 | 0.78 | NR2C2 (0.65) | NR2C2TAB1NFKB1NFKB2RELA | |
| SCHEMBL31681845 | 0.76 | SMG1 (0.51) | NR2C2TAB1NFKB1NFKB2RELA | |
| SCHEMBL2375211 | 0.76 | SMG1 (0.51) | NR2C2TAB1NFKB1NFKB2RELA | |
| SCHEMBL3950037 | 0.73 | CAMK2D (0.65) | KDRIGF1RALKMTORSMG1 | |
| SCHEMBL3949225 | 0.72 | CAMK2D (0.67) | KDRALKMTORSMG1CDK2 | |
| SCHEMBL15022537 | 0.69 | ALK (0.86) | IGF1RALK | |
| SCHEMBL22860794 | 0.67 | POLB (0.61) | KDRSMG1CDK2MKNK1CAMK2D | |
| SCHEMBL28118781 | 0.67 | SMG1 (0.70) | NR2C2TAB1IGF1RSMG1CDK2 | |
| SCHEMBL1091212 | 0.66 | CXCR4 (0.68) | NR2C2TAB1NFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3623374-A1 | STEM CELL CULTURES | The Scripps Research Institute (US) | 2020-03-18 | — | — | EP | disclosed |
| EP-3441394-A1 | STEM CELL CULTURES | The Scripps Research Institute (US) | 2019-02-13 | — | — | EP | disclosed |