Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | AMY1A | P0DUB6 | 3/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CLK1 | P49759 | 2/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.41 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.41 |
| ▸ | CLK2 | P49760 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.41 |
| ▸ | TRPC3 | Q13507 | 4/20 | 0.41 |
| ▸ | TRPC6 | Q9Y210 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24180555 | 0.82 | LMNA (0.36) | MAPTLMNAMAPK1GAAALDH1A1 | |
| SCHEMBL2373449 | 0.77 | AMY1A (0.57) | MAPTLMNAMAPK1AMY1ACHEK1 | |
| SCHEMBL13116110 | 0.75 | AMY1A (0.58) | MAPTLMNAMAPK1AMY1ACHEK1 | |
| SCHEMBL29332847 | 0.74 | BRD4 (0.40) | LMNAALDH1A1HPGD | |
| SCHEMBL12560881 | 0.71 | AMY1A (0.62) | MAPTAMY1ACHEK1MEN1KMT2A | |
| SCHEMBL2373924 | 0.71 | NAMPT (0.57) | MAPTLMNAMAPK1AMY1AMEN1 | |
| SCHEMBL24776615 | 0.71 | MAPT (0.37) | MAPTLMNAMAPK1GAAALDH1A1 | |
| SCHEMBL24180547 | 0.70 | MAPT (0.49) | MAPTLMNAMAPK1AMY1ACHEK1 | |
| SCHEMBL13342146 | 0.69 | AMY1A (0.60) | MAPTAMY1ACHEK1MEN1KMT2A | |
| SCHEMBL14214492 | 0.69 | AMY1A (0.61) | MAPTLMNAMAPK1AMY1AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3936508-A1 | A COMPOSITION COMPRISING STEM CELL CULTURES | The Scripps Research Institute (US) | 2022-01-12 | — | — | EP | disclosed |
| EP-3623374-A1 | STEM CELL CULTURES | The Scripps Research Institute (US) | 2020-03-18 | — | — | EP | disclosed |
| EP-3441394-A1 | STEM CELL CULTURES | The Scripps Research Institute (US) | 2019-02-13 | — | — | EP | disclosed |