Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 10/20 | 0.52 |
| ▸ | MAP2K2 | P36507 | 9/20 | 0.52 |
| ▸ | GAA | P10253 | 6/20 | 0.47 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16672384 | 0.89 | GAA (0.61) | MAP2K1MAP2K2GAACREBBPMEN1 | |
| SCHEMBL20726622 | 0.84 | MAP2K1 (0.46) | MAP2K1MAP2K2GAAHDAC3HDAC4 | |
| SCHEMBL16672404 | 0.83 | GAA (0.60) | GAACREBBPMEN1HTTKMT2A | |
| SCHEMBL20726633 | 0.80 | GAA (0.46) | GAACREBBPMEN1HTTKMT2A | |
| SCHEMBL16672412 | 0.79 | CREBBP (0.49) | GAACREBBPHDAC3HDAC4HDAC1 | |
| SCHEMBL16672421 | 0.79 | CREBBP (0.39) | MAP2K1MAP2K2GAACREBBPMEN1 | |
| SCHEMBL20726631 | 0.79 | PTGS2 (0.57) | GAACREBBPMEN1HTTKMT2A | |
| SCHEMBL16672386 | 0.78 | CREBBP (0.40) | MAP2K1MAP2K2GAACREBBPMEN1 | |
| SCHEMBL20726634 | 0.77 | GAA (0.56) | GAACREBBPMEN1KMT2AALDH1A1 | |
| SCHEMBL16672326 | 0.77 | MAPT (0.47) | GAACREBBPMEN1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3060549-B1 | NOVEL ANTIFUNGAL OXODIHYDROPYRIDINECARBOHYDRAZIDE DERIVATIVE | DAE WOONG PHARMA (KR) | 2019-02-13 | — | — | EP | disclosed |