Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 8/20 | 0.46 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 9/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20726635 | 0.84 | MAP2K1 (0.52) | MAP2K1MAP2K2GAAMEN1KMT2A | |
| SCHEMBL20726657 | 0.79 | HDAC3 (0.38) | GAAHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL16672407 | 0.78 | GAA (0.55) | GAAKMT2AMAPT | |
| SCHEMBL20726653 | 0.76 | PTGS2 (0.53) | GAAMEN1KMT2ABRD4MAPT | |
| SCHEMBL20726643 | 0.74 | GAA (0.49) | GAAGFERMEN1KMT2ABRD4 | |
| SCHEMBL16672384 | 0.72 | GAA (0.61) | MAP2K1MAP2K2GAAMEN1KMT2A | |
| SCHEMBL20726641 | 0.68 | LMNA (0.45) | MEN1KMT2ABRD4MAPT | |
| SCHEMBL12814358 | 0.67 | GAA (0.45) | MAP2K1MAP2K2GAAGFERTDP1 | |
| SCHEMBL16672404 | 0.67 | GAA (0.60) | GAAGFERMEN1KMT2AMAPT | |
| SCHEMBL27679442 | 0.67 | MAP2K1 (0.78) | MAP2K1MAP2K2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3060549-B1 | NOVEL ANTIFUNGAL OXODIHYDROPYRIDINECARBOHYDRAZIDE DERIVATIVE | DAE WOONG PHARMA (KR) | 2019-02-13 | — | — | EP | disclosed |