Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 5/20 | 0.77 |
| ▸ | YWHAG | P61981 | 1/20 | 0.68 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.52 |
| ▸ | MET | P08581 | 3/20 | 0.50 |
| ▸ | IAPP | P10997 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7568170 | 0.87 | APP (1.00) | APPYWHAGALOX5METIAPP | |
| Hydroxytyrosol Butanoate SCHEMBL31729490 | 0.86 | APP (0.79) | APPYWHAGALOX5METIAPP | |
| Hydroxytyrosol Butanoate SCHEMBL17299395 | 0.86 | APP (0.79) | APPYWHAGALOX5METIAPP | |
| SCHEMBL28150655 | 0.86 | APP (0.84) | APPYWHAGALOX5METIAPP | |
| SCHEMBL3274537 | 0.85 | APP (0.68) | APPYWHAGALOX5IAPPMAPT | |
| SCHEMBL18898045 | 0.84 | APP (0.75) | APPYWHAGALOX5IAPPMAPT | |
| SCHEMBL23088822 | 0.83 | APP (0.69) | APPYWHAGALOX5METIAPP | |
| SCHEMBL12300533 | 0.83 | APP (0.78) | APPYWHAGALOX5METLMNA | |
| SCHEMBL15760492 | 0.83 | APP (0.73) | APPYWHAGALOX5METIAPP | |
| SCHEMBL12246761 | 0.82 | APP (0.83) | APPYWHAGALOX5METIAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019033010-A1 | USE OF PHENOLIC COMPOUNDS FROM OLEA EUROPAEA | MCCORD DARLENE E (US) | 2019-02-14 | — | — | WO | disclosed |