Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 1.00 |
| ▸ | YWHAG | P61981 | 1/20 | 0.76 |
| ▸ | IAPP | P10997 | 3/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | TYR | P14679 | 1/20 | 0.53 |
| ▸ | IGF1R | P08069 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | MET | P08581 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12246764 | 0.94 | APP (0.88) | APPYWHAGIAPPALOX5TDP1 | |
| SCHEMBL490480 | 0.92 | APP (1.00) | APPYWHAGIAPPALOX5TDP1 | |
| SCHEMBL28150655 | 0.92 | APP (0.84) | APPYWHAGIAPPALOX5TDP1 | |
| SCHEMBL22353624 | 0.92 | APP (0.84) | APPYWHAGIAPPALOX5TDP1 | |
| SCHEMBL12246761 | 0.91 | APP (0.83) | APPYWHAGIAPPALOX5TDP1 | |
| SCHEMBL22577544 | 0.91 | APP (0.83) | APPYWHAGIAPPALOX5TDP1 | |
| Hydroxytyrosol Butanoate SCHEMBL17299395 | 0.89 | APP (0.79) | APPYWHAGIAPPALOX5KDM4E | |
| Hydroxytyrosol Butanoate SCHEMBL31729490 | 0.89 | APP (0.79) | APPYWHAGIAPPALOX5KDM4E | |
| SCHEMBL12300533 | 0.89 | APP (0.78) | APPYWHAGALOX5MET | |
| SCHEMBL20730239 | 0.87 | APP (0.77) | APPYWHAGIAPPALOX5ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10640450-B1 | Hydroxytyrosol dihydrocaffeate having antioxidant activity and a method for preparing the same | SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2020-05-05 | — | — | US | disclosed |
| US-10640450-B1 | Hydroxytyrosol dihydrocaffeate having antioxidant activity and a method for preparing the same | SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2020-05-05 | — | — | US | disclosed |
| US-9089499-B2 | Para-coumaric acid or para-hydroxycinnamic acid derivatives and their use in cosmetic or dermatological compositions | UNIVERSITE JOSEPH FOURIER-GRENOBLE 1 (FR) | 2015-07-28 | — | — | US | disclosed |
| US-9089499-B2 | Para-coumaric acid or para-hydroxycinnamic acid derivatives and their use in cosmetic or dermatological compositions | UNIVERSITE JOSEPH FOURIER-GRENOBLE 1 (FR) | 2015-07-28 | — | — | US | disclosed |
| US-20130272983-A1 | Para-Coumaric Acid or Para-Hydroxycinnamic Acid Derivatives and their Use in Cosmetic or Dermatological Compositions | Universite Joseph Fourier-Grenoble 1. (FR) | 2013-10-17 | — | — | US | disclosed |
| US-20130272983-A1 | Para-Coumaric Acid or Para-Hydroxycinnamic Acid Derivatives and their Use in Cosmetic or Dermatological Compositions | Universite Joseph Fourier-Grenoble 1. (FR) | 2013-10-17 | — | — | US | disclosed |
| US-8481593-B2 | Para-coumaric acid or para-hydroxycinnamic acid derivatives and their use in cosmetic or dermatological compositions | BASF BEAUTY CARE SOLUTIONS S.A.S. (FR) | 2013-07-09 | — | — | US | disclosed |
| US-8481593-B2 | Para-coumaric acid or para-hydroxycinnamic acid derivatives and their use in cosmetic or dermatological compositions | BASF BEAUTY CARE SOLUTIONS S.A.S. (FR) | 2013-07-09 | — | — | US | disclosed |
| US-20110237551-A1 | Para-Coumaric Acid or Para-Hydroxycinnamic Acid Derivatives and Their Use in Cosmetic or Dermatological Compositions | BASF BEAUTY CARE SOLUTIONS FRANCE S.A.S. (FR) | 2011-09-29 | — | — | US | disclosed |
| US-20110237551-A1 | Para-Coumaric Acid or Para-Hydroxycinnamic Acid Derivatives and Their Use in Cosmetic or Dermatological Compositions | BASF BEAUTY CARE SOLUTIONS FRANCE S.A.S. (FR) | 2011-09-29 | — | — | US | disclosed |
| US-20070183996-A1 | Para-coumaric acid or para-hydroxycinnamic acid derivatives and their use in cosmetic or dermatological compositions | BASF BEAUTY CARE SOLUTIONS FRANCE S.A.S. (FR) | 2007-08-09 | — | — | US | disclosed |
| US-20070183996-A1 | Para-coumaric acid or para-hydroxycinnamic acid derivatives and their use in cosmetic or dermatological compositions | BASF BEAUTY CARE SOLUTIONS FRANCE S.A.S. (FR) | 2007-08-09 | — | — | US | disclosed |
| EP-0809493-B1 | A METHOD FOR THE TREATMENT OF HYPERPROLIFERATIVE EPITHELIAL SKIN DISEASES BY TOPICAL APPLICATION OF HYDROXYLATED AROMATIC PROTEIN CROSS-LINKING COMPOUNDS | US HEALTH (US) | 2002-09-11 | — | — | EP | disclosed |
| US-5610185-A | Method for the treatment of hyperproliferative epithelial skin diseases by topical application of hydroxylated aromatic protein cross-linking compounds | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1997-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110237551-A1 | Para-Coumaric Acid or Para-Hydroxycinnamic Acid Derivatives and Their Use in Cosmetic or Dermatological Compositions | TYR, CUTA, HPD | APP 2129/4885YWHAG 602/4885IAPP 4863/4885 |
| US-10640450-B1 | Hydroxytyrosol dihydrocaffeate having antioxidant activity and a method for preparing the same | COMT, QDPR, DHODH | APP 1724/4885YWHAG 4541/4885IAPP 2312/4885 |
| US-20070183996-A1 | Para-coumaric acid or para-hydroxycinnamic acid derivatives and their use in cosmetic or dermatological compositions | TYR, CUTA, HPD | APP 2180/4885YWHAG 580/4885IAPP 4870/4885 |
| US-20130272983-A1 | Para-Coumaric Acid or Para-Hydroxycinnamic Acid Derivatives and their Use in Cosmetic or Dermatological Compositions | TYR, CUTA, HPD | APP 2180/4885YWHAG 580/4885IAPP 4870/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.