Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.68 |
| ▸ | IAPP | P10997 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.55 |
| ▸ | YWHAG | P61981 | 1/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.54 |
| ▸ | TYR | P14679 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Naphthalene SCHEMBL5397697 | 0.92 | APP (0.59) | APPIAPPMAPTHIF1AHSD17B10 | |
| SCHEMBL27972225 | 0.86 | APP (0.51) | APPIAPPMAPTHIF1AHSD17B10 | |
| SCHEMBL18269500 | 0.86 | ALOX5 (0.53) | APPIAPPALDH1A1ALOX5OR51E2 | |
| SCHEMBL20730239 | 0.85 | APP (0.77) | APPIAPPMAPTHIF1AHSD17B10 | |
| SCHEMBL23582361 | 0.85 | GAA (0.54) | APPIAPPMAPTHSD17B10KDM4E | |
| SCHEMBL1746504 | 0.85 | ALOX5 (0.51) | APPIAPPMAPTHIF1AHSD17B10 | |
| SCHEMBL4190020 | 0.85 | APP (0.50) | APPIAPPALDH1A1ALOX5OR51E2 | |
| SCHEMBL1745477 | 0.85 | CA2 (0.52) | APPIAPPALDH1A1ALOX5OR51E2 | |
| SCHEMBL30716575 | 0.85 | ALOX5 (0.51) | APPIAPPMAPTHIF1AHSD17B10 | |
| Dihydroferulic Acid Methyl Ester SCHEMBL490876 | 0.85 | ALOX5 (0.77) | ALDH1A1LMNAALOX5OR51E2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107721614-B | Special organic fertilizer for peach trees and preparation method thereof | 北京联合大学 | 2021-05-25 | — | — | CN | disclosed |
| WO-2021030174-A1 | TRUNCATED ITRACONAZOLE ANALOGUES AND METHODS OF USE THEREOF | UNIVERSITY OF CONNECTICUT (US) | 2021-02-18 | — | — | WO | disclosed |
| CN-107569645-B | Mongolian medicine for regulating stomach and intestine and its preparing method | 内蒙古民族大学附属医院 | 2021-01-15 | — | — | CN | disclosed |
| CN-107582899-B | Mongolian medicine for clearing heat and stopping bleeding and its preparing process | 内蒙古民族大学附属医院 | 2021-01-15 | — | — | CN | disclosed |
| US-10765748-B2 | Composition and methods for tethering bioactive peptides to metal oxide surfaces | UNIVERSITY OF AKRON (US) | 2020-09-08 | — | — | US | disclosed |
| US-10414864-B2 | Degradable amino acid-based poly (ester urea) copolymer adhesives | THE UNIVERSITY OF AKRON (US) | 2019-09-17 | — | — | US | disclosed |
| US-10414864-B2 | Degradable amino acid-based poly (ester urea) copolymer adhesives | THE UNIVERSITY OF AKRON (US) | 2019-09-17 | — | — | US | disclosed |
| CN-107721614-A | A kind of peach fertilizer special for organic and preparation method thereof | 北京联合大学 | 2018-02-23 | — | — | CN | disclosed |
| CN-107582899-A | The anaesthetic and its manufacturing process of a kind of clearing away heat to stop bleeding | 内蒙古民族大学附属医院 | 2018-01-16 | — | — | CN | disclosed |
| US-20170210852-A1 | DEGRADABLE AMINO ACID-BASED POLY (ESTER UREA) COPOLYMER ADHESIVES | THE UNIVERSITY OF AKRON (US) | 2017-07-27 | — | — | US | disclosed |
| WO-2008144602-A1 | DEUTERATED ZAMIFENACIN DERIVATIVES | AUSPEX PHARMACEUTICALS, INC. (US) | 2008-11-27 | — | — | WO | disclosed |
| EP-1157989-B1 | FLUORIDES OF 4-SUBSTITUTED PIPERIDINE DERIVATIVES | EISAI CO LTD (JP) | 2004-09-22 | — | — | EP | disclosed |
| EP-1115738-A4 | SYNTHESIS OF CYCLIC PEPTIDES | UNIV QUEENSLAND (AU) | 2004-09-01 | — | — | EP | disclosed |
| US-6677330-B1 | ACETYLCHOLINESTERASE INHIBITORS; TREATING ALZHEIMER*S DISEASE, ATTENTION DEFICIT, HYPERACTIVITY AND BRAIN DISORDERS | EISAI CO., LTD. (JP) | 2004-01-13 | — | — | US | disclosed |
| EP-1157989-A1 | FLUORIDES OF 4-SUBSTITUTED PIPERIDINE DERIVATIVES | Eisai Co., Ltd. (JP) | 2001-11-28 | — | — | EP | disclosed |
| EP-1115738-A1 | SYNTHESIS OF CYCLIC PEPTIDES | THE UNIVERSITY OF QUEENSLAND (AU) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000018790-A1 | SYNTHESIS OF CYCLIC PEPTIDES | THE UNIVERSITY OF QUEENSLAND (AU) | 2000-04-06 | — | — | WO | disclosed |
| EP-0473084-B1 | Polyethylene glycol derivatives, their modified peptides, methods for producing them and use of the modified peptides | SUMITOMO PHARMA (JP) | 1995-11-15 | — | — | EP | disclosed |
| US-5183660-A | Drugs having decreased antigenicity, delayed biological clearance and exhibit physiological activity over a long period | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1993-02-02 | — | — | US | disclosed |
| EP-0473084-A2 | Polyethylene glycol derivatives, their modified peptides, methods for producing them and use of the modified peptides | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1992-03-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10765748-B2 | Composition and methods for tethering bioactive peptides to metal oxide surfaces | PTMS, CALCB, CALCA | APP 562/4885IAPP 333/4885MAPT 2884/4885 |
| US-20170210852-A1 | DEGRADABLE AMINO ACID-BASED POLY (ESTER UREA) COPOLYMER ADHESIVES | PNMT, UBE3A, PCNA | APP 1109/4885IAPP 1882/4885MAPT 710/4885 |
| US-10414864-B2 | Degradable amino acid-based poly (ester urea) copolymer adhesives | PNMT, UBE3A, PCNA | APP 1109/4885IAPP 1882/4885MAPT 710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.