⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL435993 | 0.81 | LMNA (0.33) | — | |
| SCHEMBL20730760 | 0.77 | CYP2C19 (0.32) | — | |
| SCHEMBL438907 | 0.75 | LMNA (0.37) | — | |
| SCHEMBL20730797 | 0.75 | LMNA (0.32) | — | |
| SCHEMBL20730796 | 0.70 | SMYD3 (0.32) | — | |
| SCHEMBL25158086 | 0.69 | MEN1 (0.33) | — | |
| SCHEMBL277921 | 0.68 | LMNA (0.45) | — | |
| SCHEMBL13995390 | 0.68 | XPO1 (0.34) | — | |
| SCHEMBL19728162 | 0.67 | SAT1 (0.55) | — | |
| SCHEMBL25278640 | 0.67 | LMNA (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019032941-A1 | LINCOSAMIDE ANTIBIOTICS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-02-14 | — | — | WO | disclosed |