Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.66 |
| ▸ | CA12 | O43570 | 2/20 | 0.62 |
| ▸ | CA2 | P00918 | 2/20 | 0.62 |
| ▸ | CA9 | Q16790 | 2/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | GBA1 | P04062 | 1/20 | 0.57 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13251389 | 0.95 | ALDH1A1 (0.64) | ALDH1A1CA12CA2CA9ALOX15 | |
| SCHEMBL5741229 | 0.94 | ALDH1A1 (0.62) | ALDH1A1CA12CA2CA9ALOX15 | |
| SCHEMBL19362573 | 0.94 | ALDH1A1 (0.62) | ALDH1A1CA12CA2CA9ALOX15 | |
| SCHEMBL20327817 | 0.90 | ALDH1A1 (0.62) | ALDH1A1CA12CA2CA9ALOX15 | |
| SCHEMBL7094852 | 0.86 | ALDH1A1 (0.79) | ALDH1A1CA12CA2CA9ALOX15 | |
| SCHEMBL7201051 | 0.86 | ALDH1A1 (0.86) | ALDH1A1CA12CA2CA9ALOX15 | |
| SCHEMBL20730794 | 0.85 | ALDH1A1 (0.70) | ALDH1A1CA2MEN1KMT2ATSHR | |
| SCHEMBL18966907 | 0.85 | ALDH1A1 (0.68) | ALDH1A1TSHRLMNANPSR1 | |
| SCHEMBL7093365 | 0.84 | ALDH1A1 (0.77) | ALDH1A1CA12CA2CA9ALOX15 | |
| SCHEMBL7097551 | 0.84 | ALDH1A1 (0.77) | ALDH1A1CA12CA2CA9ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019032941-A1 | LINCOSAMIDE ANTIBIOTICS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-02-14 | — | — | WO | disclosed |