Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 4/20 | 0.42 |
| ▸ | GRM3 | Q14832 | 4/20 | 0.42 |
| ▸ | FABP7 | O15540 | 1/20 | 0.34 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19508460 | 1.00 | GRM2 (0.42) | GRM2GRM3FABP7FABP5SLC6A3 | |
| SCHEMBL20730984 | 1.00 | GRM2 (0.42) | GRM2GRM3FABP7FABP5SLC6A3 | |
| SCHEMBL20731962 | 1.00 | GRM2 (0.42) | GRM2GRM3FABP7FABP5SLC6A3 | |
| SCHEMBL20722251 | 0.86 | GRM2 (0.55) | GRM2GRM3FABP7FABP5NAAA | |
| SCHEMBL19508459 | 0.79 | GRM2 (0.34) | GRM2GRM3MAPTMEN1KMT2A | |
| SCHEMBL20730986 | 0.79 | GRM2 (0.34) | GRM2GRM3MAPTMEN1KMT2A | |
| SCHEMBL19508648 | 0.76 | NAAA (0.35) | GRM2GRM3NAAA | |
| SCHEMBL19177219 | 0.74 | GRM2 (0.36) | GRM2GRM3MEN1KMT2AALDH1A1 | |
| SCHEMBL8892415 | 0.73 | PPARG (0.34) | GRM2GRM3SLC6A3MAPTMEN1 | |
| SCHEMBL7392780 | 0.72 | GRM2 (0.46) | GRM2GRM3FABP7FABP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10689327-B2 | Prodrug amino acid derivative | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2020-06-23 | — | — | US | disclosed |
| US-10464884-B2 | Prodrug of amino acid derivative | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2019-11-05 | — | — | US | disclosed |
| US-20190047943-A1 | PRODRUG OF AMINO ACID DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2019-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10689327-B2 | Prodrug amino acid derivative | GRIN2A, SLC1A2, SLC1A1 | GRM2 12/4885GRM3 26/4885FABP7 111/4885 |
| US-10464884-B2 | Prodrug of amino acid derivative | GRIN2A, SLC1A2, SLC1A1 | GRM2 13/4885GRM3 28/4885FABP7 114/4885 |
| US-20190047943-A1 | PRODRUG OF AMINO ACID DERIVATIVE | GRIN2A, SLC1A2, SLC1A1 | GRM2 13/4885GRM3 28/4885FABP7 114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.