Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23938017 | 0.81 | USP2 (0.31) | USP2GAAMAPTALOX15GFER | |
| SCHEMBL24729634 | 0.81 | GAA (0.40) | USP2GAAMAPTALOX15GFER | |
| SCHEMBL23938015 | 0.72 | USP2 (0.33) | USP2GAAMAPTALOX15GFER | |
| SCHEMBL20731142 | 0.68 | GAA (0.38) | GAAMAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL20731029 | 0.64 | TLR8 (0.38) | GAAMAPTHSD17B10 | |
| SCHEMBL16879368 | 0.63 | SMN1; SMN2 (0.41) | USP2GAAMAPTALOX15GFER | |
| SCHEMBL651969 | 0.60 | NUDT1 (0.31) | USP2GAAMAPTALOX15GFER | |
| Hydrochloric Acid SCHEMBL23292054 | 0.59 | MEN1 (0.44) | USP2GAAMAPTALOX15GFER | |
| SCHEMBL24588297 | 0.59 | USP2 (0.39) | USP2GAAMAPTALOX15GFER | |
| SCHEMBL22576486 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020033707-A1 | CARBOXAMIDES AS UBIQUITIN-SPECIFIC PROTEASE INHIBITORS | FORMA THERAPEUTICS, INC. (US) | 2020-02-13 | — | — | WO | disclosed |
| WO-2019032863-A1 | CARBOXAMIDES AS UBIQUITIN-SPECIFIC PROTEASE INHIBITORS | FORMA THERAPEUTICS, INC. (US) | 2019-02-14 | — | — | WO | disclosed |