Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20731986 | 0.81 | USP2 (0.32) | USP2GAAMAPTALOX15GFER | |
| SCHEMBL24729634 | 0.78 | GAA (0.40) | USP2GAAMAPTALOX15GFER | |
| SCHEMBL23938071 | 0.71 | HSD17B10 (0.35) | GAAMAPTALOX15HSD17B10 | |
| SCHEMBL23938015 | 0.69 | USP2 (0.33) | USP2GAAMAPTALOX15GFER | |
| SCHEMBL23938070 | 0.67 | TLR8 (0.36) | GAA | |
| SCHEMBL651969 | 0.58 | NUDT1 (0.31) | USP2GAAMAPTALOX15GFER | |
| Hydrochloric Acid SCHEMBL23292054 | 0.57 | MEN1 (0.44) | USP2GAAMAPTALOX15GFER | |
| SCHEMBL24588297 | 0.57 | USP2 (0.39) | USP2GAAMAPTALOX15GFER | |
| SCHEMBL22576486 | 0.56 | — | — | |
| SCHEMBL16879368 | 0.56 | SMN1; SMN2 (0.41) | USP2GAAMAPTALOX15GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210323975-A1 | CARBOXAMIDES AS UBIQUITIN-SPECIFIC PROTEASE INHIBITORS | VALO EARLY DISCOVERY, INC. | 2021-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210323975-A1 | CARBOXAMIDES AS UBIQUITIN-SPECIFIC PROTEASE INHIBITORS | USP28, USP25, USP24 | USP2 6/4885GAA 699/4885MAPT 2661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.