Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Citric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 3/20 | 0.89 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Citric Acid SCHEMBL10949557 | 1.00 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL3644532 | 0.97 | CA4 (0.94) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL10952183 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL4191523 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL1135949 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL25311384 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL5077427 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL5011330 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL1136109 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL5030693 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 17364 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4746864-A1 | C5 KETONE COMPOSITIONS AND RELATED METHODS FOR TREATING METABOLIC DYSFUNCTION | Keto Innovations, LLC (US) | 2026-05-27 | — | — | EP | claimed |
| CN-122079120-A | Porous carbon, silicon-carbon anode material comprising porous carbon, and preparation method and application of porous carbon | — | 2026-05-26 | — | — | CN | claimed |
| CN-122094704-A | Formulations for oral administration of active agents comprising a combination of acid-neutralizing polymer and non-polymeric material | — | 2026-05-26 | — | — | CN | claimed |
| CN-122091575-A | Bimetallic ion doped sodium vanadium fluorophosphate positive electrode material and preparation method thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122074633-A | Flavour composition, aqueous food composition containing said flavour composition, preparation and use thereof | — | 2026-05-26 | — | — | CN | claimed |
| WO-2026105164-A1 | NON-AQUEOUS LIQUID FORMULATIONS OF TETRACYCLINE ANTIBIOTICS | ETICO LIFESCIENCES PRIVATE LIMITED (IN) | 2026-05-21 | — | — | WO | claimed |
| WO-2026106919-A1 | ENERGY BOOSTING AND MOBILITY INDUCING FORMULATION FOR ANIMALS INCLUDING PETS | JONES MARGARET (US) | 2026-05-21 | — | — | WO | claimed |
| EP-4743405-A1 | PROCESSES FOR PRODUCING CALCIUM OXIDE AND SULFURIC ACID FROM CALCIUM SULFATE WITH MAGNESIUM INTERMEDIATE | Innovator Energy Llc (US) | 2026-05-20 | — | — | EP | claimed |
| US-12629323-B2 | Cosmetic kit and its use as a make-up product | Oxygen Innovation SRL (IT) | 2026-05-19 | — | — | US | claimed |
| CN-122059396-A | Modified phenolic resin-based hard carbon material applied to sodium ion battery, preparation method of modified phenolic resin-based hard carbon material and sodium ion battery anode material | 山东炜林新能源科技有限公司 | 2026-05-19 | — | — | CN | claimed |
| US-4453553-A | For use with steam | COHN CHARLES C | 1984-06-12 | — | — | US | claimed |
| US-4368134-A | HEAVY DUTY LAUNDRY DETERGENTS | COLGATE PALMOLIVE COMPANY (US) | 1983-01-11 | — | — | US | claimed |
| EP-0059113-A2 | Improved bacterial growth medium and method of growing bacteria | STATE OF OREGON BY AND THROUGH THE OREGON STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIVERSITY (US) | 1982-09-01 | — | — | EP | claimed |
| US-4321079-A | Aqueous sulfur dispersion having reduced corrosive activity toward ferrous metal | STANDARD OIL COMPANY (INDIANA) (US) | 1982-03-23 | — | — | US | claimed |
| US-4294718-A | SODIUM CARBONATE-BICARBONATE-SILICATE, CITRIC ACID OR SALT AND MAGNESIUM SULFATE | COLGATE-PALMOLIVE COMPANY (US) | 1981-10-13 | — | — | US | claimed |
| US-4269744-A | COMPRISING A METAL SALT OF A FATTY ACID, DI- OR TRIPENTAERYTHRITOL OR A MIXTURE WITH PENTAERYTHRITOL, MANNITOL, AND/OR SORBITOL, AND A MAGNESIUM COMPOUND; SYNERGISTIC; DISCOLORATION INHIBITION | DART INDUSTRIES INC. (US) | 1981-05-26 | — | — | US | claimed |
| US-4256691-A | ZINC OR MAGNESIUM COMPOUNDS IN AMMONIA | STANDARD OIL COMPANY (INDIANA) (US) | 1981-03-17 | — | — | US | claimed |
| US-4085209-A | PLANT FUNGICIDES | ROHM AND HAAS COMPANY (US) | 1978-04-18 | — | — | US | claimed |
| US-4040838-A | NON-POLLUTING BLEACH OR BLIX SOLUTION; METAL COMPLEX OF ORGANIC ACID, AMMONIUM COMPOUND, MAGNESIUM COMPOUND | FUJI PHOTO FILM CO., LTD. (JA) | 1977-08-09 | — | — | US | claimed |
| US-3964255-A | Method of inflating an automobile passenger restraint bag | SPECIALTY PRODUCTS DEVELOPMENT CORPORATION (US) | 1976-06-22 | — | — | US | claimed |