Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24567501 | 0.82 | FAAH (0.35) | TOP2ATOP2BMEN1KMT2AFAAH | |
| SCHEMBL14583669 | 0.82 | FAAH (0.35) | TOP2ATOP2BMEN1KMT2AFAAH | |
| SCHEMBL19936024 | 0.80 | TOP2A (0.33) | TOP2ATOP2BMEN1KMT2AFAAH | |
| SCHEMBL21711063 | 0.79 | ALDH1A1 (0.37) | TOP2ATOP2BFAAHNAAAPOLB | |
| SCHEMBL19288356 | 0.78 | GAA (0.38) | TOP2ATOP2BMEN1KMT2AFAAH | |
| SCHEMBL10846532 | 0.78 | TOP2A (0.38) | TOP2ATOP2BALDH1A1 | |
| SCHEMBL25805083 | 0.78 | ALDH1A1 (0.31) | TOP2ATOP2BPOLBALDH1A1 | |
| SCHEMBL16178016 | 0.77 | ADORA2A (0.33) | TOP2ATOP2BALDH1A1 | |
| SCHEMBL16061311 | 0.77 | ADORA2A (0.33) | TOP2ATOP2BALDH1A1 | |
| SCHEMBL16059003 | 0.77 | ADORA2A (0.33) | TOP2ATOP2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200361910-A1 | PROCESS TO PREPARE PROPYLENE AMINES AND PROPYLENE AMINE DERIVATIVES | NOURYON CHEMICALS INTERNATIONAL B.V. (NL) | 2020-11-19 | — | — | US | disclosed |
| WO-2019030197-A1 | PROCESS TO PREPARE PROPYLENE AMINES AND PROPYLENE AMINE DERIVATIVES | AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) | 2019-02-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200361910-A1 | PROCESS TO PREPARE PROPYLENE AMINES AND PROPYLENE AMINE DERIVATIVES | HRH3, HRH4, HRH1 | TOP2A 4625/4885TOP2B 4394/4885MEN1 1127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.