SCHEMBL20733744

SCHEMBL20733744

c1ccc(-c2nnc3c(n2)c2c(c4ccccc4n2-c2ccccc2)c2c4ccccc4n(-c4ccccc4)c32)cc1

nearest known ligand 0.51

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 2/20 0.42
▸ KDM4E B2RXH2 1/20 0.42
▸ ATM Q13315 1/20 0.42
▸ KMT2A Q03164 2/20 0.37
▸ IL1R1 P14778 1/20 0.37
▸ MEN1 O00255 1/20 0.36
▸ ALDH1A1 P00352 1/20 0.36
▸ MAPT P10636 1/20 0.36
▸ HTT P42858 1/20 0.36
▸ NPC1 O15118 1/20 0.35
▸ MAPK1 P28482 1/20 0.35
▸ RAB9A P51151 1/20 0.35
▸ AVPR1A P37288 1/20 0.35
▸ KDM4C Q9H3R0 1/20 0.34
▸ CCNE1 P24864 1/20 0.34
▸ CDK2 P24941 1/20 0.34
▸ ABCG2 Q9UNQ0 1/20 0.33
▸ RXFP1 Q9HBX9 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20733782 0.92 L3MBTL1 (0.40) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL20733855 0.86 L3MBTL1 (0.40) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL20733859 0.81 KDM4E (0.37) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL25068857 0.80 TUBB4A (0.35) L3MBTL1KDM4EATMKMT2AMEN1
SCHEMBL20733717 0.80 CYP1A2 (0.38) L3MBTL1KDM4EATMALDH1A1MAPT
SCHEMBL20733858 0.80 KDM4E (0.41) L3MBTL1KDM4EATMALDH1A1MAPT
SCHEMBL25068856 0.80 L3MBTL1 (0.43) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL17123116 0.78 L3MBTL1 (0.46) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL17123113 0.77 L3MBTL1 (0.44) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL20733873 0.77 KDM4E (0.36) L3MBTL1KDM4EATMALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230057590-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2023-02-23 — — US disclosed
US-20190051842-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2019-02-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230057590-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OXER1 L3MBTL1 803/4885KDM4E 655/4885ATM 4475/4885
US-20190051842-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OXER1 L3MBTL1 803/4885KDM4E 655/4885ATM 4475/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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