Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 12/20 | 0.57 |
| ▸ | MAPT | P10636 | 7/20 | 0.57 |
| ▸ | TP53 | P04637 | 6/20 | 0.57 |
| ▸ | USP2 | O75604 | 5/20 | 0.57 |
| ▸ | SLCO1B3 | Q9NPD5 | 2/20 | 0.51 |
| ▸ | SLCO1B1 | Q9Y6L6 | 2/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Obacunone SCHEMBL564187 | 0.85 | CYP3A4 (0.79) | CYP3A4MAPTTP53USP2SLCO1B3 | |
| Obacunone SCHEMBL20733839 | 0.85 | CYP3A4 (0.79) | CYP3A4MAPTTP53USP2SLCO1B3 | |
| SCHEMBL22040140 | 0.85 | CYP3A4 (0.56) | CYP3A4MAPTTP53USP2SLCO1B3 | |
| Obacunone SCHEMBL18324167 | 0.85 | CYP3A4 (0.79) | CYP3A4MAPTTP53USP2SLCO1B3 | |
| SCHEMBL19480414 | 0.77 | CYP3A4 (0.73) | CYP3A4MAPTTP53USP2SLCO1B3 | |
| Deacetoxy-7-Oxogedunin SCHEMBL20639417 | 0.73 | CYP3A4 (1.00) | CYP3A4MAPTTP53USP2SLCO1B3 | |
| Deacetoxy-7-Oxogedunin SCHEMBL12998441 | 0.73 | CYP3A4 (1.00) | CYP3A4MAPTTP53USP2SLCO1B3 | |
| SCHEMBL19629724 | 0.72 | CYP3A4 (0.44) | CYP3A4MAPTTP53USP2SLCO1B3 | |
| SCHEMBL31507072 | 0.72 | HSP90AA1 (0.58) | CYP3A4MAPTTP53USP2SLCO1B3 | |
| SCHEMBL18871689 | 0.69 | CYP3A4 (0.74) | CYP3A4MAPTTP53USP2SLCO1B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10632100-B2 | Application of obacunone in preparation of drug for preventing and treating lung damage and pulmonary fibrosis | GUANGDONG PROVINCIAL HOSPITAL OF TRADITIONAL CHINESE MEDICINE (CN) | 2020-04-28 | — | — | US | disclosed |
| US-20190046502-A1 | APPLICATION OF OBACUNONE IN PREPARATION OF DRUG FOR PREVENTING AND TREATING LUNG DAMAGE AND PULMONARY FIBROSIS | GUANGDONG PROVINCIAL HOSPITAL OF TRADITIONAL CHINESE MEDICINE (CN) | 2019-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190046502-A1 | APPLICATION OF OBACUNONE IN PREPARATION OF DRUG FOR PREVENTING AND TREATING LUNG DAMAGE AND PULMONARY FIBROSIS | BCL2L10, CCL11, BMP1 | CYP3A4 3256/4885MAPT 4789/4885TP53 1808/4885 |
| US-10632100-B2 | Application of obacunone in preparation of drug for preventing and treating lung damage and pulmonary fibrosis | BCL2L10, CCL11, BMP1 | CYP3A4 3256/4885MAPT 4789/4885TP53 1808/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.