Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 4/20 | 0.46 |
| ▸ | PLA2G4A | P47712 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TNKS | O95271 | 1/20 | 0.44 |
| ▸ | TOP2A | P11388 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 2/20 | 0.41 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17853268 | 0.97 | PLA2G2A (0.49) | PLA2G2APLA2G4AKDM4EMEN1NPC1 | |
| SCHEMBL10109627 | 0.91 | MAOB (0.46) | PLA2G2APLA2G4AKDM4EMEN1NPC1 | |
| SCHEMBL17987954 | 0.91 | NPC1 (0.45) | PLA2G2APLA2G4AKDM4EMEN1NPC1 | |
| SCHEMBL15747045 | 0.89 | MAPT (0.49) | KDM4EMEN1NPC1ALDH1A1MAPT | |
| SCHEMBL25612247 | 0.88 | MMP12 (0.45) | PLA2G2APLA2G4AKDM4EMEN1NPC1 | |
| SCHEMBL10307269 | 0.87 | PLA2G2A (0.48) | PLA2G2APLA2G4AKDM4EMEN1NPC1 | |
| SCHEMBL74934 | 0.87 | PLA2G2A (0.48) | PLA2G2APLA2G4AKDM4EMEN1NPC1 | |
| SCHEMBL6372717 | 0.87 | PLA2G2A (0.48) | PLA2G2APLA2G4AKDM4EMEN1NPC1 | |
| SCHEMBL15496373 | 0.87 | PLA2G2A (0.48) | PLA2G2APLA2G4AKDM4EMEN1NPC1 | |
| SCHEMBL6372452 | 0.87 | PLA2G2A (0.48) | PLA2G2APLA2G4AKDM4EMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019031605-A1 | FUSED RING COMPOUND | 東ソー株式会社 | 2019-02-14 | — | — | WO | disclosed |