Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 18/20 | 0.38 |
| ▸ | FGFR4 | P22455 | 9/20 | 0.38 |
| ▸ | KDR | P35968 | 8/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | FGFR2 | P21802 | 5/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16246296 | 1.00 | FGFR1 (0.38) | FGFR1FGFR4KDRMEN1KMT2A | |
| SCHEMBL16246006 | 0.87 | MEN1 (0.38) | FGFR1FGFR4KDRMEN1KMT2A | |
| SCHEMBL16246372 | 0.85 | FGFR4 (0.42) | FGFR1FGFR4FGFR2 | |
| SCHEMBL30089813 | 0.85 | FGFR4 (0.42) | FGFR1FGFR4FGFR2 | |
| SCHEMBL20733930 | 0.84 | FGFR1 (0.44) | FGFR1FGFR4KDRFGFR2 | |
| SCHEMBL20733929 | 0.82 | FGFR1 (0.37) | FGFR1FGFR4KDRMEN1KMT2A | |
| SCHEMBL29545761 | 0.82 | FGFR1 (0.37) | FGFR1FGFR4KDRMEN1KMT2A | |
| SCHEMBL16071669 | 0.82 | FGFR1 (0.41) | FGFR1FGFR4MEN1KMT2AFGFR2 | |
| SCHEMBL29546028 | 0.81 | FGFR4 (0.39) | FGFR1FGFR4KDRFGFR2 | |
| SCHEMBL20733932 | 0.81 | FGFR1 (0.36) | FGFR1FGFR4KDRFGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109384790-B | Fibroblast growth factor receptor inhibitors and uses thereof | 药捷安康(南京)科技股份有限公司 | 2022-05-10 | — | — | CN | disclosed |