Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 19/20 | 0.36 |
| ▸ | FGFR4 | P22455 | 7/20 | 0.36 |
| ▸ | KDR | P35968 | 6/20 | 0.36 |
| ▸ | FGFR2 | P21802 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29546202 | 1.00 | FGFR1 (0.36) | FGFR1FGFR4KDRFGFR2 | |
| SCHEMBL20733930 | 0.83 | FGFR1 (0.44) | FGFR1FGFR4KDRFGFR2 | |
| SCHEMBL20734021 | 0.82 | FGFR1 (0.40) | FGFR1FGFR4FGFR2 | |
| SCHEMBL29545501 | 0.81 | FGFR1 (0.38) | FGFR1FGFR4KDRFGFR2 | |
| SCHEMBL16246296 | 0.81 | FGFR1 (0.38) | FGFR1FGFR4KDRFGFR2 | |
| SCHEMBL20733929 | 0.80 | FGFR1 (0.37) | FGFR1FGFR4KDRFGFR2 | |
| SCHEMBL29545761 | 0.80 | FGFR1 (0.37) | FGFR1FGFR4KDRFGFR2 | |
| SCHEMBL29546028 | 0.79 | FGFR4 (0.39) | FGFR1FGFR4KDRFGFR2 | |
| SCHEMBL20733957 | 0.74 | FGFR1 (0.54) | FGFR1FGFR4KDRFGFR2 | |
| SCHEMBL21783933 | 0.73 | FGFR1 (0.55) | FGFR1FGFR4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019029541-A1 | FIBROBLAST GROWTH FACTOR RECEPTOR INHIBITOR AND USE THEREOF | 南京药捷安康生物科技有限公司 | 2019-02-14 | — | — | WO | disclosed |