Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XPO1 | O14980 | 2/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10328385 | 0.69 | — | — | |
| SCHEMBL22493260 | 0.66 | MAOB (0.41) | CES1DAGLA | |
| SCHEMBL23219799 | 0.65 | CES1 (0.39) | CES1 | |
| SCHEMBL23219780 | 0.65 | CHRNA4 (0.34) | — | |
| Bromide SCHEMBL25255658 | 0.63 | — | — | |
| SCHEMBL23219807 | 0.60 | DPP4 (0.34) | — | |
| SCHEMBL21469421 | 0.60 | — | — | |
| SCHEMBL14446927 | 0.60 | — | — | |
| SCHEMBL15297680 | 0.60 | — | — | |
| Formic Acid SCHEMBL25258506 | 0.59 | CES1 (0.36) | CES1DAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019032743-A1 | COMPOUNDS, COMPOSITIONS AND METHODS | DENALI THERAPEUTICS INC. (US) | 2019-02-14 | — | — | WO | disclosed |