Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2177382 | 0.98 | — | — | |
| Formic Acid SCHEMBL25258506 | 0.90 | CES1 (0.36) | — | |
| SCHEMBL21469421 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL7556827 | 0.74 | — | — | |
| SCHEMBL11034181 | 0.74 | — | — | |
| SCHEMBL22493260 | 0.67 | MAOB (0.41) | — | |
| SCHEMBL30404225 | 0.67 | CES1 (0.39) | — | |
| SCHEMBL9435356 | 0.65 | — | — | |
| SCHEMBL27228706 | 0.65 | NOTUM (0.55) | — | |
| SCHEMBL20734150 | 0.63 | XPO1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125907-A1 | DEGRADATION OF BRUTON'S TYROSINE KINASE (BTK) BY CONJUGATION OF BTK INHIBITORS WITH E3 LIGASE LIGAND AND METHODS OF USE | BEIGENE, LTD. (KY) | 2023-07-06 | — | — | WO | disclosed |