Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VHL | P40337 | 2/20 | 0.51 |
| ▸ | CTSC | P53634 | 3/20 | 0.49 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2073322 | 0.89 | CTSC (0.46) | VHLCTSCSCD5OPRM1OPRD1 | |
| SCHEMBL2073323 | 0.89 | CTSC (0.46) | VHLCTSCSCD5OPRM1OPRD1 | |
| SCHEMBL2074016 | 0.89 | CTSC (0.51) | VHLCTSCOPRM1OPRD1OPRK1 | |
| SCHEMBL3772312 | 0.87 | CTSC (0.53) | VHLCTSCOPRM1OPRD1OPRK1 | |
| SCHEMBL2072010 | 0.86 | CTSC (0.66) | CTSC | |
| SCHEMBL2075246 | 0.82 | VHL (0.51) | VHLOPRM1OPRD1OPRK1XIAP | |
| SCHEMBL12422472 | 0.80 | CTSC (0.47) | CTSCSCD5 | |
| SCHEMBL2074846 | 0.80 | CTSC (0.48) | VHLCTSCOPRM1OPRD1OPRK1 | |
| SCHEMBL2074847 | 0.80 | CTSC (0.48) | VHLCTSCOPRM1OPRD1OPRK1 | |
| SCHEMBL3690891 | 0.80 | VHL (0.52) | VHLCTSCOPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110201581-A1 | Novel Compounds 010 | ASTRAZENECA AB (SE) | 2011-08-18 | — | — | US | disclosed |
| US-7902181-B2 | Compounds 010 | ASTRAZENECA AB (SE) | 2011-03-08 | — | — | US | disclosed |
| US-20090306042-A1 | Novel Compounds 010 | ASTRAZENECA AB (SE) | 2009-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306042-A1 | Novel Compounds 010 | MRGPRX2, F12, TBXA2R | VHL 4069/4885CTSC 3209/4885SCD5 3705/4885 |
| US-20110201581-A1 | Novel Compounds 010 | MRGPRX2, F12, TBXA2R | VHL 4069/4885CTSC 3209/4885SCD5 3705/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.