Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VHL | P40337 | 1/20 | 0.52 |
| ▸ | CTSC | P53634 | 8/20 | 0.48 |
| ▸ | CTSK | P43235 | 2/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7858105 | 0.89 | VHL (0.47) | VHLCTSCCTSKOPRM1OPRD1 | |
| SCHEMBL3701201 | 0.86 | CTSC (0.65) | CTSCCTSK | |
| SCHEMBL2075246 | 0.80 | VHL (0.51) | VHLOPRM1OPRD1OPRK1XIAP | |
| SCHEMBL2073451 | 0.80 | VHL (0.51) | VHLCTSCOPRM1OPRD1OPRK1 | |
| SCHEMBL3692633 | 0.78 | VHL (0.57) | VHLOPRM1OPRD1OPRK1XIAP | |
| SCHEMBL4398641 | 0.77 | VHL (0.51) | VHLOPRM1OPRD1OPRK1XIAP | |
| SCHEMBL2071996 | 0.77 | VHL (0.54) | VHLOPRM1OPRD1OPRK1XIAP | |
| SCHEMBL2072259 | 0.76 | VHL (0.48) | VHLOPRM1OPRD1OPRK1XIAP | |
| SCHEMBL7857586 | 0.76 | CTSC (0.60) | CTSCCTSK | |
| SCHEMBL2074016 | 0.76 | CTSC (0.51) | VHLCTSCOPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010142985-A1 | SUBSTITUTED N-[1-CYANO-2-(PHENYL)ETHYL]PIPERIDIN-2-YLCARBOXMIDE COMPOUNDS 761 | ASTRAZENECA AB (SE) | 2010-12-16 | — | — | WO | disclosed |