SCHEMBL20735397

SCHEMBL20735397

c1ccc2c(c1)nc1oc3c(-c4ccc5c(c4)c4cccc6c4-c4c(ccnc4c4ccccc4c4cccnc64)c4ccccc45)nccc3n12

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20735374 0.85 PRKDC (0.30)
SCHEMBL20735396 0.76 FLT3 (0.37) POLBHPGD
SCHEMBL22929988 0.75 KDM4E (0.31) POLBHPGD
SCHEMBL20697969 0.73 FLT3 (0.36) POLBHPGD
SCHEMBL20735519 0.72 ALOX5 (0.37)
SCHEMBL20735542 0.71 NPC1 (0.33) POLBHPGD
SCHEMBL20735398 0.69 NPC1 (0.34) HPGD
SCHEMBL20735546 0.69 HSD17B10 (0.36) POLBHPGD
SCHEMBL22930018 0.68 KDM4E (0.34)
SCHEMBL24379793 0.67 NPC1 (0.34) POLBHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11349083-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-05-31 US disclosed
US-20190051843-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2019-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190051843-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES BMP4, CTCF, ORC3 POLB 1183/4885HPGD 2450/4885
US-11349083-B2 Organic electroluminescent materials and devices BMP4, CTCF, ORC3 POLB 1183/4885HPGD 2450/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.