SCHEMBL20737305

SCHEMBL20737305

CCCc1nc2ccccc2n1-c1cccc(-c2ccc3cc4c(cc3c2)C2(c3ccccc3-c3ccccc32)c2c-4ccc3ccccc23)c1

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.39
PDE10A Q9Y233 4/20 0.38
CYP1A2 P05177 2/20 0.38
PPARG P37231 7/20 0.35
MEN1 O00255 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
KMT2A Q03164 1/20 0.33
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.33
MAPT P10636 1/20 0.32
MAPK10 P53779 1/20 0.32
FLT3 P36888 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20735955 0.96 PDE10A (0.39) USP2PDE10ACYP1A2PPARGMEN1
SCHEMBL20735933 0.94 PDE10A (0.39) USP2PDE10ACYP1A2PPARGMEN1
SCHEMBL20737306 0.93 PDE10A (0.36) USP2PDE10ACYP1A2MEN1KMT2A
SCHEMBL20736523 0.92 PDE10A (0.42) USP2PDE10ACYP1A2PPARGMAPT
SCHEMBL20737120 0.92 PDE10A (0.40) USP2PDE10ACYP1A2PPARGMEN1
SCHEMBL20737753 0.90 PDE10A (0.39) USP2PDE10ACYP1A2PPARGMEN1
SCHEMBL27250539 0.89 USP2 (0.39) USP2PDE10ACYP1A2PPARGMEN1
SCHEMBL20735956 0.89 PDE10A (0.37) PDE10ACYP1A2MEN1KMT2AMAPT
SCHEMBL27250420 0.89 USP2 (0.39) USP2PDE10ACYP1A2PPARGMEN1
SCHEMBL27250576 0.88 PDE10A (0.37) USP2PDE10ACYP1A2PPARGMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12022728-B2 Organic electroluminescent element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2024-06-25 US disclosed
US-11552251-B2 Organic electroluminescent element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2023-01-10 US disclosed
US-20190051835-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2019-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11552251-B2 Organic electroluminescent element and electronic device L1CAM, ESR1, LEF1 USP2 4455/4885PDE10A 4099/4885CYP1A2 739/4885
US-20190051835-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE L1CAM, ESR1, LEF1 USP2 4455/4885PDE10A 4099/4885CYP1A2 739/4885
US-12022728-B2 Organic electroluminescent element and electronic device L1CAM, ESR1, LEF1 USP2 4455/4885PDE10A 4099/4885CYP1A2 739/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.