SCHEMBL20737306

SCHEMBL20737306

CCc1nc2ccccc2n1-c1cccc(-c2ccc3cc4c(cc3c2)C2(c3ccccc3-c3ccccc32)c2c-4ccc3ccccc23)c1

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 5/20 0.36
CYP1A2 P05177 2/20 0.36
MAPK10 P53779 1/20 0.34
FLT3 P36888 2/20 0.33
MAPT P10636 3/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
KMT2A Q03164 1/20 0.32
USP2 O75604 1/20 0.31
BMI1 P35226 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20735956 0.96 PDE10A (0.37) PDE10ACYP1A2MAPK10MAPTKDM4E
SCHEMBL20735938 0.94 PDE10A (0.37) PDE10ACYP1A2MAPK10FLT3MAPT
SCHEMBL20737305 0.93 USP2 (0.39) PDE10ACYP1A2MAPK10FLT3MAPT
SCHEMBL20736520 0.92 PDE10A (0.40) PDE10ACYP1A2MAPK10MAPTKDM4E
SCHEMBL20737116 0.91 PDE10A (0.37) PDE10ACYP1A2MAPK10FLT3MAPT
SCHEMBL20737316 0.91 MAPK1 (0.40) PDE10ACYP1A2MAPK10FLT3ALDH1A1
SCHEMBL20737748 0.90 PDE10A (0.37) PDE10ACYP1A2MAPK10MAPTKDM4E
SCHEMBL20736974 0.89 PDE10A (0.36) PDE10ACYP1A2MAPK10FLT3MAPT
SCHEMBL20735955 0.89 PDE10A (0.39) PDE10ACYP1A2MAPK10MAPTMEN1
SCHEMBL20737307 0.89 ESR1 (0.38) PDE10AMAPK10FLT3MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12022728-B2 Organic electroluminescent element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2024-06-25 US disclosed
US-11552251-B2 Organic electroluminescent element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2023-01-10 US disclosed
US-20190051835-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2019-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11552251-B2 Organic electroluminescent element and electronic device L1CAM, ESR1, LEF1 PDE10A 4099/4885CYP1A2 739/4885MAPK10 2523/4885
US-20190051835-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE L1CAM, ESR1, LEF1 PDE10A 4099/4885CYP1A2 739/4885MAPK10 2523/4885
US-12022728-B2 Organic electroluminescent element and electronic device L1CAM, ESR1, LEF1 PDE10A 4099/4885CYP1A2 739/4885MAPK10 2523/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.