SCHEMBL20737692

SCHEMBL20737692

c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4ccc5c6c(ccc5c4)-c4cc5ccccc5cc4C64c5ccccc5-c5ccccc54)c3)n2)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 11/20 0.34
HSD17B1 P14061 3/20 0.34
HSD17B2 P37059 3/20 0.34
MEN1 O00255 4/20 0.33
ALDH1A1 P00352 4/20 0.33
KMT2A Q03164 4/20 0.33
KDM4E B2RXH2 3/20 0.33
MAPT P10636 3/20 0.33
HPGD P15428 3/20 0.33
CYP1A2 P05177 2/20 0.33
TP53 P04637 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
HSD17B10 Q99714 2/20 0.33
LMNA P02545 1/20 0.33
GLA P06280 1/20 0.33
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2B6 P20813 1/20 0.32
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20736575 0.98 MEN1 (0.35) PDK2HSD17B1HSD17B2MEN1ALDH1A1
SCHEMBL20736576 0.97 PDK2 (0.38) PDK2HSD17B1HSD17B2MEN1ALDH1A1
SCHEMBL20735877 0.96 PDK2 (0.34) PDK2HSD17B1HSD17B2MEN1ALDH1A1
SCHEMBL20736003 0.94 ALDH1A1 (0.34) PDK2HSD17B1HSD17B2MEN1ALDH1A1
SCHEMBL20737691 0.92 MEN1 (0.41) PDK2HSD17B1HSD17B2MEN1ALDH1A1
SCHEMBL27250748 0.92 ALDH1A1 (0.36) PDK2MEN1ALDH1A1KMT2AKDM4E
SCHEMBL20737730 0.91 MEN1 (0.40) PDK2MEN1ALDH1A1KMT2AKDM4E
SCHEMBL20737734 0.91 MEN1 (0.40) PDK2HSD17B1HSD17B2MEN1ALDH1A1
SCHEMBL20736570 0.91 MEN1 (0.40) PDK2HSD17B1HSD17B2MEN1ALDH1A1
SCHEMBL20736574 0.91 MEN1 (0.40) PDK2HSD17B1HSD17B2MEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12022728-B2 Organic electroluminescent element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2024-06-25 US disclosed
US-11552251-B2 Organic electroluminescent element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2023-01-10 US disclosed
US-20190051835-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2019-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11552251-B2 Organic electroluminescent element and electronic device L1CAM, ESR1, LEF1 PDK2 2420/4885HSD17B1 2518/4885HSD17B2 2878/4885
US-20190051835-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE L1CAM, ESR1, LEF1 PDK2 2420/4885HSD17B1 2518/4885HSD17B2 2878/4885
US-12022728-B2 Organic electroluminescent element and electronic device L1CAM, ESR1, LEF1 PDK2 2420/4885HSD17B1 2518/4885HSD17B2 2878/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.